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Escin

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Definition: Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.     
Pharmacological Action Cardiovascular Agents 		Other names Aescin; opinobiomo; opino biomo; beta Escin; beta Aescin; opino-biomo; biomo Brand of Escin; beta-Escin; beta-Aescin; Sankyo Brand of Escin; Reparil; Madaus Brand of Escin; Flebostasin; Feparil; Fepalitan; Opino; Eskuzan; Escina; Aescusan
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
escin Ib  0   *Escin. Life Sci 2000 ;66(23):2233-8
escin Ia  0   *Escin. Bioorg Med Chem 1998 Jul;6(7):1019-23
escin IIa  0   *Escin. Bioorg Med Chem 1998 Jul;6(7):1019-23
venostasin  0   *Escin *Plant Extracts Drug Combinations. Vasa 1983;12(4):377
Venex Gel  80106-45-2 Venex Gel  *Escin *Heparinoids *Nylidrin Drug Combinations. Praxis 1981;70(14):612
recto-reparil  79234-29-0 Escin, mixt. with belladonna and 2-(dimethylamino)ethyl 4-(butylamino)benzoate  *Belladonna Alkaloids *Escin *Tetracaine Drug Combinations. G Clin Med 59(11):1978
Essaven Gel  77430-02-5 Essaven gel  *Escin *Heparin *Phospholipids Drug Combinations Gels. Arch Immunol Therap Experiment 24(6):807;1976
essaven  8067-31-0   *Escin *Hesperidin *Phosphatidylcholines Drug Combinations. Praxis 65(32):994;1976; Praxis 65(32):997;1976
Urol (pharmaceutical)  97503-06-5   *Escin *Plant Extracts Drug Combinations. Med Welt 27(40):1908;1976
escin, ethyleneglycol monosalicylate, heparin drug combination  0   *Escin *Heparin *Salicylates Drug Combinations. Z Allg Med 51(14):684;1975
aescorin  8054-09-9 Vitamin E mixt. with Aesculus hippocastanum ext., 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride monohydrochloride & 3-((6-O-(6-deoxy-alpha-L-manno pyranosyl)-beta-D-glucopyranosyl)oxy)-2-(3,4- dihydroxyphenyl)  *Escin *Esculin *Rutin *Vitamin E Drug Combinations. Neurol Neurochir Pol 11(4):457;1977
Vasoforte  78837-96-4 beta-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1), (R)-, mixt. with 3-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one and escin  *Escin *Pantothenic Acid *Rutin Drug Combinations Vascular Diseases/drug therapy. Z Allg Med 49(23):1103;1973
aspririn, bamethan, escin drug combination  77124-31-3 Benzoic acid, 2-(acetyloxy)-, mixt. with alpha-((butylamino)methyl)-4-hydroxybenzenemethanol and escin  *Aspirin *Escin *Ethanolamines *Phenethylamines Drug Combinations. Med Welt 24(33):33;1974
Reparil Gel  0   *Escin *Salicylates Drug Combinations. Lille Med 17(11)(suppl 8):1612;1972
Phlebex  37317-65-0   *Escin *Camphor *Pentosan Sulfuric Polyester Drug Combinations. Z Hautkr 47(23):939;1972
Ultra-demoplas  59030-22-7   *Escin *Antipyrine *Dexamethasone *Phenylbutazone *Thiamine *Vitamin B 6 Glucocorticoids Vitamin B Complex. Med Welt 23(43):1557;1972; Z Allg Med 51(25):1097;1975
escin, flavonoid, phospholipid drug combination  0   *Escin *Flavonoids *Phospholipids Drug Combinations. Munch Med Wochenschr 114(32):1420;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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