encyclopedia of medical concepts
ψ
ψ
Cytochalasins
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Definition
: 11- to 14-membered macrocyclic lactones with a fused isoindolone. Members with INDOLES attached at the C10 position are called chaetoglobosins. They are produced by various fungi. Some members interact with ACTIN and inhibit CYTOKINESIS.
/antag permitted but consider also ANTITOXINS
Examples
Cytochalasin B
;
Cytochalasin D
Substance
CAS Registry & name
Categories
Source
Drugs
*
10-
phenyl-
(12)-
cytochalasins Z17
0
*Cytochalasins
Alkaloids.
Planta Med. 2010 Oct;76(14):1616-21
10-
phenyl-
(12)-
cytochalasins Z16
0
*Cytochalasins
Alkaloids.
Planta Med. 2010 Oct;76(14):1616-21
xylarisin
0
*Cytochalasins.
Chem Pharm Bull (Tokyo). 2009 Dec;57(12):1409-11
cytochalasin Z11
0
*Cytochalasins.
Chem Biodivers 2009 May;6(5):739-45
cytochalasin Z10
0
*Cytochalasins.
Chem Biodivers 2009 May;6(5):739-45
cytochalasin Z9
0
*Cytochalasins.
J Nat Prod 2006 Jun;69(6):871-5
cytochalasin Z8
0
*Cytochalasins.
J Nat Prod 2006 Jun;69(6):871-5
cytochalasin Z7
0
*Cytochalasins.
J Nat Prod 2006 Jun;69(6):871-5
aspochalasin L
0
*Cytochalasins
HIV Integrase/antagonists & inhibitors.
J Antibiot (Tokyo) 2005 Apr;58(4):279-83
aspochalamin B
0
*Cytochalasins.
J Antibiot (Tokyo). 2004 Nov;57(11):707-14
aspochalamin C
0
*Cytochalasins.
J Antibiot (Tokyo). 2004 Nov;57(11):707-14
aspochalamin D
0
*Cytochalasins.
J Antibiot (Tokyo). 2004 Nov;57(11):707-14
aspochalamin A
0
*Cytochalasins.
J Antibiot (Tokyo). 2004 Nov;57(11):707-14
19,20-
epoxycytochalasin Q
0
*Cytochalasins.
J Nat Prod 2004 Jun;67(6):1036-8
aspochalasin I
0
*Cytochalasins.
J Nat Prod 2004 Mar;67(3):328-32
aspochalasin K
0
*Cytochalasins.
J Nat Prod 2004 Mar;67(3):328-32
aspochalasin J
0
*Cytochalasins.
J Nat Prod 2004 Mar;67(3):328-32
cytochalasin Z6
0
*Cytochalasins.
J Nat Prod 2003 Dec;66(12):1540-4
cytochalasin Z5
0
*Cytochalasins.
J Nat Prod 2003 Dec;66(12):1540-4
cytochalasin Z4
0
*Cytochalasins.
J Nat Prod 2003 Dec;66(12):1540-4
cytochalasin Z
0
*Cytochalasins.
J Nat Prod 2002 Sep;65(9):1274-7
cytochalasin Y
0
*Cytochalasins.
J Nat Prod 2002 Sep;65(9):1274-7
cytochalasin X
0
*Cytochalasins.
J Nat Prod 2002 Sep;65(9):1274-7
aspochalasin H
0
*Cytochalasins.
J Antibiot (Tokyo) 2002 Jul;55(7):666-8
aspochalasin D
0
Cytochalasins.
J Antibiot (Tokyo) 2001 Apr;54(4):379-81
N1445
0
*Cytochalasins
Caspase 1/antagonists & inhibitors.
Cancer J Sci Am 1999 Sep-Oct;5(5):293-300
aspochalasin G
0
Cytochalasins.
Jpn J Antibiot 1997 Nov;50(11):919-25
aspochalasin F
0
Cytochalasins.
Jpn J Antibiot 1997 Nov;50(11):919-25
RKS 1778
0
*Cytochalasins.
J Nat Prod 1997 Jul;60(7):669-72
cytochalasin J
0
*Cytochalasins.
Cell Motil Cytoskeleton 1997;36(2):112-24
cytochalasin W
0
*Cytochalasins.
Nat Toxin 1996;4(2):53-7
aspochalasin E
0
Cytochalasins.
J Antibiot (Tokyo) 1993 Apr;46(4):679-81
18-
dehydroxycytochalasin H
141994-72-1 1H-
Cycloundec(d)isoindol-
1-
one, 15-
(acetyloxy)-
2,3,3a,4,5,6,6a,9,10,11,12,15-
dodecahydro-
6-
hydroxy-
4,10,12-
trimethyl-
5-
methylene-
3-
(phenylmethyl)-
, (3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12R*,13E,15S*,15aS*)
*Cytochalasins
*Isoindoles.
J Antibiot (Tokyo) 1992 May;45(5):679-85
cytochalasin H
53760-19-3
*Cytochalasins.
Exp Cell Biol 1982;50(3):155
cytochalasin H(2)B
74409-92-0 24-
Oxa(14)cytochalasa-
6(12),13,21-
triene-
1,23-
dione, 7,20-
dihydroxy-
16-
methyl-
10-
phenyl-
, dihydro deriv., (7S,13E,16R,20R,21E)
*Cytochalasins.
Biochim Biophys Acta 1981;676(3):338
cytochalasin C
22144-76-9
*Cytochalasins.
J Biol Chem 1981;256(16):8663
cytochalasin A
14110-64-6
*Cytochalasins.
J Cyclic Nucleotide Res 1981;7(1):1
deacetylcytochalasin H
53760-20-6
*Cytochalasins.
J Agric Food Chem 1981;29(1):205
proxiphomine
52212-92-7
*Cytochalasins.
Helv Chim Acta 56(7):2387;1973
protophomine
52212-93-8
*Cytochalasins.
Helv Chim Acta 56(7):2387;1973
deoxaphomine
51053-39-5 7S,16R,20R-
7,20-
dihydroxy-
16-
methyl-
10-
phenyl-
(13)cytochalasa-
6(12),13(t),21(t)-
tri ene-
1,23-
dione
*Cytochalasins.
Helv Chim Acta 56(3):966;1973
cytochalasin E
36011-19-5
*Cytochalasins
Mycotoxins
Toxins, Biological.
Pharma Action
Angiogenesis Inhibitors
J Am Chem Soc 95(16):5423;1973; Toxicol Appl Pharmacol 1980;52(2):209