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Caerulein

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Definition: A specific decapeptide obtained from the skin of Hila caerulea, an Australian amphibian. Caerulein is similar in action and composition to CHOLECYSTOKININ. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. It is used in paralytic ileus and as diagnostic aid in pancreatic malfunction.  /biosyn /physiol permitted; do not confuse X ref CERULEIN with CERULENIN    Other names Ceruletide; Cerulein; Takus; FI-6934; Ceruletid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Phe(8)-caerulein  0   *Peptide Fragments Caerulein/*analogs & derivatives. Eur J Biochem 2000 Jan;267(1):269-75
sapo, Phyllomedusa bicolor  0   Bradykinin/*analogs & derivatives Caerulein/*analogs & derivatives Drug Combinations. Toxicon 1993 Sep;31(9):1099-111
cerulein 7  20994-86-9   *Peptide Fragments Caerulein/*analogs & derivatives. Proc Natl Acad Sci USA 1987;84(14):4821
caerulein, beta-Asp(9)  81456-41-9   Caerulein/*analogs & derivatives. Peptides 1985;6 Suppl 3:29
caerulein(4-10), Nle(8)  25613-79-0 Caerulein, 1-de(5-oxo-L-proline)-2-de-L-glutamine-3-de-L-aspartic acid-8-L-norleucine  *Peptide Fragments Caerulein/*analogs & derivatives. Eur J Pharmacol 1983;94(3-4):261
caerulein, Nle(8)  65864-30-4 Caerulein, 8-L-norleucine  Caerulein/*analogs & derivatives. Eur J Pharmacol 1983;94(3-4):261
caerulein diethylamine  71247-25-1   Caerulein/*analogs & derivatives. J Nippon Med Sch 1981;48(3):370TYMTRAN

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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