encyclopedia of medical concepts
ψ
ψ
bestatin
under Leucine
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Leucine
Definition
: An essential branched-chain amino acid important for hemoglobin formation.
/biosyn /defic /physiol permitted
Other names
Leucine, L Isomer; L-
Isomer Leucine; Leucine, L-
Isomer; L-
Leucine
Substance
CAS Registry & name
Categories
Source
Drugs
*
bestatin [ 3-amino-2-hydroxy-4-phenylbutyryl-L-leucine,bestatin, (D-Leu)-(R-(R*,R*))-isomer,bestatin, (D-Leu)-(R-(R*,S*))-isomer,bestatin, (D-Leu)-(S-(R*,S*))-isomer,bestatin, (L-Leu)-(R-(R*,R*))-isomer,bestatin, (L-Leu)-(R-(R*,S*))-isomer,bestatin, (L-Leu)-(S-(R*,R*))-isomer,bestatin, (L-Leu)-(S-(R*,S*))-isomer, hydrochloride,ubenimex ]
growth inhibitor; RN given refers to ((L-Leu)-(S-(R*,S*)))-isomer; structure
58970-76-6 (3-
amino-
2-
hydroxy-
4-
phenylbutanoyl)-
L-
leucine
Leucine/*analogs & derivatives
Aminopeptidases/antagonists & inhibitors
Pharma Action
Adjuvants, Immunologic
;
Anti-Bacterial Agents
;
Antibiotics, Antineoplastic
;
Immunologic Factors
;
Protease Inhibitors
;
Anti-HIV Agents
Immunology 1979;38(1):75; Adv Exp Med Biol 1979;120B:332; Antibiotics Chemother 24:10;1978; Arch Biochem Biophys 177(1):196;1976; Biochem Biophys Res Commun 76(2):526;1977; Biochem Pharmacol 1979;28(20):3131; Cell Immunol 40(2):247;1978; J Antibiotics 29(1):97-100;1976; J Antibiotics 29(5):600;1976; J Med Chem 20(4):510;1977; Jpn J Antibiotics 30suppl:121;1977; Lloydia 40(1):67;1977; Prog Biochem Pharmacol 11:24;1976