Chromatin Assembly Factor-1 (definition)

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ψ	Chromatin Assembly Factor-1

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Definition: A histone chaperone protein that plays a role in the deposition of NUCLEOSOMES on newly synthesized DNA. It is comprised of three different subunits of 48, 60, and 150 kDa molecular size. The 48 kDa subunit, RETINOBLASTOMA-BINDING PROTEIN 4, is also a component of several other protein complexes involved in chromatin remodeling.

Examples Retinoblastoma-Binding Protein 4

Other names Chromatin Assembly Factor 1; Chromatin Assembly Complex 1, p60 Subunit; Chromatin Assembly Complex 1, p150 Subunit; Chromatin Assembly Complex 1; Assembly Factor-1, Chromatin; Assembly Complex-1, Chromatin; Chromatin Assembly Complex-1, p60 Subunit; Chromatin Assembly Complex-1, p150 Subunit; Chromatin Assembly Complex-1

Substance	Categories	Source
Chaf1b protein, mouse	*Chromatin Assembly Factor-1.
CHAF1B protein, human	*Chromatin Assembly Factor-1.
Chaf1a protein, mouse	*Chromatin Assembly Factor-1.
CHAF1A protein, human	*Chromatin Assembly Factor-1.
CAC2 protein, S cerevisiae	*Chromatin Assembly Factor-1.
RLF2 protein, S cerevisiae	*Chromatin Assembly Factor-1.
MSI1 protein, S cerevisiae	DNA-Binding Proteins Saccharomyces cerevisiae Proteins *Chromatin Assembly Factor-1.	Proc Natl Acad Sci USA 1989;86(22):8778

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

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