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Histone Demethylases
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Definition
: Enzymes that catalyse the removal of methyl groups from LYSINE or ARGININE residues found on HISTONES. Many histone demethylases generally function through an oxidoreductive mechanism.
Examples
Jumonji Domain-Containing Histone Demethylases
Other names
Lysine Demethylases, Histone; Demethylases, Histone Lysine; Demethylases, Histone Arginine; Demethylases, Histone; Arginine Demethylases, Histone; Histone Lysine Demethylases; Histone Arginine Demethylases
Substance
CAS Registry & name
Categories
Source
Drugs
*
JMJD2A protein, mouse
EC 1.14.11.-
*Histone Demethylases.
J Clin Invest 2011 Jun 1;121(6):2447-56
LSD1 protein, rat
EC 1.14.11.-
*Histone Demethylases.
Neurosci Res 2010 Sep;68(1):66-72
KIAA1718 protein, mouse
EC 1.14.11.-
*Histone Demethylases.
Genes Cells 2010 Aug;15(8):867-73
PHF8 protein, mouse
EC 1.14.11.27
*Transcription Factors
*Histone Demethylases.
Cell Res. 2010 Aug;20(8):908-18
PHF8 protein, zebrafish
EC 1.14.11.-
*Transcription Factors
*Zebrafish Proteins
*Histone Demethylases.
Nature. 2010 Jul 22;466(7305):503-7
KDM8 protein, human
EC 1.14.11.-
*Histone Demethylases.
Proc Natl Acad Sci U S A 2010 May 25;107(21):9671-6
KDM4A protein, Drosophila
EC 1.5.-
*Drosophila Proteins
*Histone Demethylases.
Mol Cell 2008 Dec 5;32(5):696-706
UTX protein, human
EC 1.14.11.-
*Nuclear Proteins
*Histone Demethylases.
Science 2007 Oct 19;318(5849):447-50
PHF8 protein, human
EC 1.14.11.-
*Transcription Factors
*Histone Demethylases
Mental Retardation, X-Linked.
J Med Genet 2005 Oct;42(10):780-6
KDM1A protein, human
EC 1.5.-
*Histone Demethylases.
Cell 2004 Dec 29;119(7):941-53
GIS1 protein, S cerevisiae
EC 1.14.11.-
*Saccharomyces cerevisiae Proteins
*Histone Demethylases.
Mol Cell Biol 1999 Nov;19(11):7630-8
RPH1 protein, S cerevisiae
0
*Repressor Proteins
*Saccharomyces cerevisiae Proteins
*Histone Demethylases.
Mol Cell Biol 1999 Nov;19(11):7630-8
KDM5D protein, human
EC 1.14.11.-
*Histone Demethylases.
Science 1995 Sep 15;269(5230):1588-90