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Histamine H3 Antagonists

More information in Books or onNLM PubMed
Definition: Drugs that selectively bind to but do not activate HISTAMINE H3 RECEPTORS. They have been used to correct SLEEP DISORDERS and MEMORY DISORDERS.      Other names H3 Blockers, Histamine; H3 Antihistaminics; H3 Antagonists, Histamine; Blockers, Histamine H3; Antagonists, Histamine H3; Histamine H3 Blockers; Histamine H3 Receptor Antagonists; Antihistaminics, H3
Substances having this pharmacologic action: ciproxifan; clobenpropit; thioperamide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-fluoro-3-(3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl)-N-(2-methylpropyl)cyclobutanecarboxamide  0   *Cyclobutanes *Pyrrolidines Histamine H3 Antagonists. J Med Chem. 2011 Nov 10;54(21):7602-20.
N-ethyl-3-fluoro-3-(3-fluoro-4-(pyrrolidinylmethyl)phenyl)cyclobutanecarboxamide  0   *Cyclobutanes *Pyrrolidines Histamine H3 Antagonists. J Med Chem. 2011 Nov 10;54(21):7602-20.
(4-cyclobutyl-(1,4)diazepan-1-yl)-(6-(4-fluorophenoxy)pyridin-3-yl)methanone  0   *Azepines *Pyridines Histamine H3 Antagonists. Bioorg Med Chem Lett 2010 Jul 15;20(14):4210-4
GSK 835726  0   *Naphthalenes *Piperidines Histamine H3 Antagonists. Expert Opin Ther Pat 2011 Mar;21(3):425-9
4-(3-(methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol  0   *Naphthols *Pyrrolidines Norepinephrine Plasma Membrane Transport Proteins/antagonists & inhibitors Histamine H3 Antagonists. J Med Chem 2010 Nov 11;53(21):7869-73

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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