Receptors (definition)

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Receptors, CXCR3

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Definition: CXCR receptors that are expressed on the surface of a number of cell types, including T-LYMPHOCYTES; NK CELLS; DENDRITIC CELLS; and a subset of B-LYMPHOCYTES. The receptors are activated by CHEMOKINE CXCL9; CHEMOKINE CXCL10; and CHEMOKINE CXCL11.

Other names Receptors, CMKBR3 Chemokine; Receptor, CXCR3; Chemokine Receptors, CMKBR3; Chemokine (C-C Motif) Receptor 3; CXCR3 Receptor; CXC Chemokine Receptors 3; CMKBR3 Chemokine Receptors; CXCR3 Receptors; CXC Chemokine Receptor 3; CD183 Antigens; Antigens, CD183

Substance	Categories	Source
N-(6-amino-1-(2,2-diphenylethylamino)-1-oxohexan-2-yl)-2-(4-oxo-4-phenylbutanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide	*Isoquinolines Receptors, CXCR3/agonists.	Biochem Biophys Res Commun. 2012 Mar 9;419(2):412-8.
N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido(2,3-d)pyrimidin-2-yl)ethyl)-N-pyridin-3-ylmethyl-2-(4-trifluoromethoxyphenyl)acetamide	Acetamides Pyrimidinones Receptors, CXCR3/antagonists & inhibitors.	Drug Metab Dispos 2009 Mar;37(3):502-13
Cxcr3 protein, rat	*Receptors, CXCR3.
Cxcr3 protein, mouse	*Receptors, CXCR3.
CXCR3 protein, human	*Receptors, CXCR3.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

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