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Nitric Oxide Synthase Type I
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Definition
: A CALCIUM-dependent, constitutively-expressed form of nitric oxide synthase found primarily in NERVE TISSUE.
Other names
nNOS Enzyme; Nitric Oxide Synthase, Type I; Neuronal Nitric Oxide Synthase; Neural Constitutive Nitric Oxide Synthase; NOS1 Protein; NCNOS Enzyme
Substance
CAS Registry & name
Categories
Source
Drugs
*
N-
(1-
(4-
(methylamino)cyclohexyl)indolin-
6-
yl)thiophene-
2-
carboximidamide
0
*Indoles
*Thiophenes
Nitric Oxide Synthase Type I/antagonists & inhibitors.
J Med Chem. 2012 Jan 26;55(2):943-55.
4-
((2-
cyclobutyl-
1H-
imidazo(4,5-
b)pyrazin-
1-
yl)methyl)-
7,8-
difluoroquinolin-
2(1H)-
one
0
*Pyrazines
*Fluoroquinolones
Nitric Oxide Synthase Type II/antagonists & inhibitors
Nitric Oxide Synthase Type I/antagonists & inhibitors.
J Med Chem 2009 May 14;52(9):3047-62
ZK 234238
0
*Oxazines
Nitric Oxide Synthase Type I/antagonists & inhibitors.
Crit Care Med 2009 Jan;37(1):208-14
N-
(4-
amino-
5-
(aminoethyl)aminopentyl)-
N'-
nitroguanidine
0
*Guanidines
*Nitro Compounds
Nitric Oxide Synthase Type I/antagonists & inhibitors.
Biochemistry 2005 Nov 22;44(46):15222-9
Nos1 protein, rat
EC 1.14.13.39
*Nitric Oxide Synthase Type I.
Nos1 protein, mouse
EC 1.14.13.39
*Nitric Oxide Synthase Type I.
NOS1 protein, human
EC 1.14.13.39
*Nitric Oxide Synthase Type I.