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ADAM Proteins

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Definition: A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain.      Other names ADAM (A Disintegrin and Metalloprotease) Proteins; A Disintegrin and Metalloprotease Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ADAMTS8 protein, rat  EC 3.4.24.-   *ADAM Proteins. Acta Anaesthesiol Scand. 2007 Feb;51(2):158-64.
ADAMTS4 protein, rat  EC 3.4.24.-   *ADAM Proteins. J Biol Chem. 2000 Jul 28;275(30):22695-703.
ADAMTS18 protein, mouse  EC 3.4.24.-   *ADAM Proteins. J Med Genet. 2011 Sep;48(9); 597-601
ADT-2 protein, C elegans  EC 3.4.24.-   *Caenorhabditis elegans Proteins *ADAM Proteins. Dev Biol. 2011 Apr 1;352(1):92-103
3-(formylhydroxyamino)-2-(3-phenyl-1-propyl)butanoic acid (2,2-dimethyl-1-methylcarbamoyl-1-propyl)amide  0   *Dipeptides *Hydroxamic Acids ADAM Proteins/antagonists & inhibitors. Blood 2003 Aug 15;102(4):1186-95
meltrin protein, Drosophila  EC 3.4.24.-   *Drosophila Proteins *ADAM Proteins. Insect Biochem Mol Biol 2010 Nov;40(11):814-23
Adamts12 protein, mouse  EC 3.4.24.-   *ADAM Proteins. Oncogene. 2010 May 20;29(20):3025-32
stall protein, Drosophila  EC 3.4.24.-   *Drosophila Proteins *ADAM Proteins. Genetics 2009 Nov;183(3):1027-40
Adamts9 protein, mouse  EC 3.4.24.-   *ADAM Proteins. Dev Cell 2009 Nov;17(5):687-98
ADAMTS19 protein, human  EC 3.4.24.-   *ADAM Proteins. Hum Reprod. 2009 Sep;24(9):2372-8
ADAM10 protein, rat  EC 3.4.24.81   *ADAM Proteins. Eur J Pharmacol 2009 May 21;610(1-3):37-41
LOC100302465 protein, rat  EC 3.4.24.-   *ADAM Proteins. Circulation 2009 May 12;119(18):2480-9
ADAM19 protein, Xenopus  EC 3.4.24.-   *Xenopus Proteins *ADAM Proteins. Mech Dev 2009 Mar-Apr;126(3-4):240-55
Adamts7 protein, rat  EC 3.4.24.-   *ADAM Proteins. Circ Res 2009 Mar 13;104(5):688-98
Adamts5 protein, rat  EC 3.4.24.-   *ADAM Proteins. Histochem Cell Biol 2006 Sep;126(3):371-80
ADAM11 protein, mouse  EC 3.4.24.-   *ADAM Proteins. Brain Res 2006 Jun 30;1097(1):39-42
Adam22 protein, rat  EC 3.4.24   *ADAM Proteins. Science 2006 Sep 22;313(5794):1792-5
ADAMTS1 protein, Xenopus  EC 3.4.24.-   *Xenopus Proteins *ADAM Proteins. Dev Biol 2006 Jul 1;295(1):26-39
Adamts13 protein, rat  EC 3.4.24.-   *ADAM Proteins. J Thromb Haemost 2006 May;4(5):1063-70
ADAMTS18 protein, human  EC 3.4.24.-   *ADAM Proteins. Biochim Biophys Acta 2006 Mar;1760(3):517-24
ADAMTS16 protein, human  EC 3.4.24.-   *ADAM Proteins. Gene 2002 Jan 23;283(1-2):49-62
Adam9 protein, rat  EC 3.4.24.-   *ADAM Proteins. Brain Res Mol Brain Res 2005 Jun 13;137(1-2):272-5
Adam28 protein, rat  EC 3.4.24.-   *ADAM Proteins. Biochem Biophys Res Commun 2005 Jun 17;331(4):1374-83
ADAMTS15 protein, human  EC 3.4.24.-   *ADAM Proteins. Prostate 2005 May 15;63(3):269-75
ADAM3A protein, human  EC 3.4.24.-   *ADAM Proteins Disintegrins.
Adam33 protein, mouse  EC 3.4.24.-   *ADAM Proteins Zinc Fingers Disintegrins.
Adamts5 protein, mouse  EC 3.4.24.-   *ADAM Proteins.
ADAM22 protein, human  EC 3.4.24.-   *Nerve Tissue Proteins *ADAM Proteins.
Adamts8 protein, mouse  EC 3.4.24.-   *ADAM Proteins.
Adam9 protein, mouse  EC 3.4.24.-   *Membrane Proteins *ADAM Proteins.
Adamts7 protein, mouse  EC 3.4.24.-   *ADAM Proteins. J Biol Chem 2004 Aug 20;279(34):35159-75
ADAMTS12 protein, human  EC 3.4.24.-   *ADAM Proteins. J Biol Chem 2004 Aug 20;279(34):35159-75
ADAMTS10 protein, human  EC 3.4.24.-   *ADAM Proteins. J Biol Chem 2004 Dec 3;279(49):51208-17
ADAM10 protein, human  EC 3.4.24.81   *Membrane Proteins *ADAM Proteins *Amyloid Precursor Protein Secretases.
Adam10 protein, mouse  EC 3.4.24.81   *Membrane Proteins *ADAM Proteins *Amyloid Precursor Protein Secretases.
Adam15 protein, mouse  EC 3.4.24.-   *Membrane Proteins *ADAM Proteins.
Adam15 protein, rat  EC 3.4.24.-   *Membrane Proteins *ADAM Proteins.
Adam8 protein, mouse  EC 3.4.24.-   *Membrane Proteins *Antigens, CD *ADAM Proteins.
Adamts1 protein, rat  EC 3.4.24.-   *ADAM Proteins.
Adamts1 protein, mouse  EC 3.4.24.-   *ADAM Proteins.
Adam28 protein, mouse  EC 3.4.24.-   *ADAM Proteins.
Adam3 protein, mouse  EC 3.4.24.-   *Membrane Glycoproteins *ADAM Proteins Disintegrins.
ADAM18 protein, human  EC 3.4.24.-   *ADAM Proteins.
Adam5 protein, rat  EC 3.4.24.-   *ADAM Proteins.
Adam7 protein, mouse  EC 3.4.24.-   *Membrane Proteins *ADAM Proteins.
Adamts20 protein, mouse  EC 3.4.24.-   *ADAM Proteins. Development 2003 Oct;130(19):4665-72
ADAMTS20 protein, human  EC 3.4.24.-   *ADAM Proteins. J Biol Chem 2003 Mar 14;278(11):9503-13
ADAM32 protein, human  EC 3.4.24.-   *ADAM Proteins Disintegrins. Gene 2003 Jan 30;304:151-62
Adam32 protein, mouse  EC 3.4.24.-   *ADAM Proteins. Gene 2003 Jan 30;304:151-62
ADAM33 protein, human  EC 3.4.24.-   *ADAM Proteins Zinc Fingers Disintegrins. Gene 2002 Jan 9;282(1-2):227-36
ADAMTS14 protein, human  EC 3.4.24.-   *ADAM Proteins. Biochim Biophys Acta 2001 Dec 30;1522(3):221-5
ADAM7 protein, human  EC 3.4.24.-   *Membrane Glycoproteins *ADAM Proteins. Biol Reprod 2001 Sep;65(3):944-50
ADAMTS3 protein, human  EC 3.4.24.-   *Procollagen N-Endopeptidase *ADAM Proteins. J Biol Chem 2001 Aug 24;276(34):31502-9
ADAMTS9 protein, human  EC 3.4.24.-   *ADAM Proteins. Genomics 2000 Aug 1;67(3):343-50
ADAM19 protein, human  EC 3.4.24.-   *ADAM Proteins Biological Markers Disintegrins. Blood 2000 Jul 15;96(2):732-9
ADAM28 protein, human  EC 3.4.24.-   *ADAM Proteins Membrane Glycoproteins Disintegrins. Biochem J 2000 May 15;348 Pt 1;21-7; Mol Hum Reprod 1999 Dec;5(12):1127-34
Adam21 protein, mouse  EC 3.4.24.-   *Membrane Proteins *ADAM Proteins. Endocrinology 2000 Jun;141(6):2033-42
ADAM30 protein, human  EC 3.4.24.-   *ADAM Proteins Membrane Proteins Disintegrins. Biochem Biophys Res Commun 1999 Oct 5;263(3):810-5
ADAM29 protein, human  EC 3.4.24.-   *ADAM Proteins Membrane Proteins Disintegrins. Biochem Biophys Res Commun 1999 Oct 5;263(3):810-5
ADAMTS7 protein, human  EC 3.4.24.-   *ADAM Proteins. J Biol Chem 1999 Sep 3;274(36):25555-63
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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