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Cyclin-Dependent Kinase Inhibitor p21

More information in Books or onNLM PubMed
Definition: A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3.     
Pharmacological Action Protein Kinase Inhibitors 		Other names Senescent Cell Derived Inhibitor Protein 1; Cyclin Dependent Kinase Inhibitor p21; Cyclin Dependent Kinase Inhibitor 1A Protein; Cdk Interacting Protein 1; CDK2 Associated Protein 20 kDa; p21 Cyclin Kinase Inhibitor; p21 Cell Cycle Regulator; Senescent Cell-Derived Inhibitor Protein 1; Cyclin-Dependent Kinase Inhibitor 1A Protein; Cyclin Kinase Inhibitor p21; Cell Cycle Regulator p21; Cdk2 Inhibitor Protein; Cdk-Interacting Protein 1; CDKN1A Protein; CDKN1 Protein; CDK2-Associated Protein 20 kDa
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Cdkn1a protein, rat  0   *Cyclin-Dependent Kinase Inhibitor p21.
Cdkn1a protein, mouse  0   *Cyclin-Dependent Kinase Inhibitor p21.
CDKN1A protein, human  0   *Cyclin-Dependent Kinase Inhibitor p21.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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