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R-SNARE Proteins

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Definition: SNARE proteins where the central amino acid residue of the SNARE motif is an ARGININE. They are classified separately from the Q-SNARE PROTEINS where the central amino acid residue of the SNARE motif is a GLUTAMINE. This subfamily contains the vesicle associated membrane proteins (VAMPs) based on similarity to the prototype for the R-SNAREs, VAMP2 (synaptobrevin 2).     
Examples Vesicle-Associated Membrane Protein 1; Vesicle-Associated Membrane Protein 2; Vesicle-Associated Membrane Protein 3 		Other names Vesicle Associated Membrane Proteins; Vesicle Associated Membrane Protein; R SNARES; R SNARE Proteins; Proteins, R-SNARE; Membrane Proteins, Vesicle-Associated; Membrane Protein, Vesicle-Associated; Vesicle-Associated Membrane Proteins; Vesicle-Associated Membrane Protein; Synaptobrevins; Synaptobrevin; R-SNARES
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Sec22B protein, human  0   *R-SNARE Proteins. Cell Host Microbe. 2012 Jan 19;11(1):46-57
VAMP722 protein, Arabidopis  0   *Arabidopsis Proteins *R-SNARE Proteins. PLoS One. 2011;6(10) (dup#6):e26129
VAMP721 protein, Arabidopis  0   *Arabidopsis Proteins *R-SNARE Proteins. PLoS One. 2011;6(10) (dup#6):e26129
Sec22 protein, Plasmodium falciparum  0   *Protozoan Proteins *R-SNARE Proteins. Eukaryot Cell. 2009 Sep;8(9):1330-40
VAMP4 protein, rat  0   *R-SNARE Proteins. J Cell Sci 2008 Sep 15;121(Pt 18):2983-91
VAP protein, Arabidopsis  0   *Arabidopsis Proteins *R-SNARE Proteins. Plant Cell 2005 Nov;17(11):3066-80
YKT61 protein, Arabidopsis  0   *Arabidopsis Proteins *R-SNARE Proteins. J Mol Biol 2005 Jul 1;350(1):92-101
Sybl1 protein, mouse  0   *R-SNARE Proteins.
Sybl1 protein, rat  0   *R-SNARE Proteins.
STXBP5L protein, mouse  0   *R-SNARE Proteins. Int J Oncol 2004 Mar;24(3):737-42
Vamp8 protein, mouse  0   *R-SNARE Proteins Nerve Tissue Proteins.
Vamp8 protein, rat  0   *R-SNARE Proteins Nerve Tissue Proteins.
YKT6 protein, human  0   *R-SNARE Proteins Carrier Proteins.
Ykt6 protein, rat  0   *R-SNARE Proteins.
VAMP5 protein, human  0   *R-SNARE Proteins.
Stxbp5 protein, rat  0   *Nerve Tissue Proteins *R-SNARE Proteins.
STXBP5 protein, human  0   *Nerve Tissue Proteins *R-SNARE Proteins.
SEC22A protein, human  0   *R-SNARE Proteins.
Vamp4 protein, mouse  0   *R-SNARE Proteins. J Biol Chem 2003 Jun 20;278(25):23046-54
VAMP4 protein, human  0   *R-SNARE Proteins. J Biol Chem 1998 Apr 24;273(17):10317-24
Syb1 protein, S pombe  0   *Schizosaccharomyces pombe Proteins *R-SNARE Proteins. Biochem Biophys Res Commun 2003 Feb 14;301(3):641-5
Sec22b protein, mouse  0   *R-SNARE Proteins. J Biol Chem 2001 Jun 29;276(26):24203-11
VAMP7 protein, human  0   *R-SNARE Proteins. J Cell Biol 1999 Aug 23;146(4):765-76; Nat Genet 1996 Jun;13(2):227-9
Vamp5 protein, mouse  0   *R-SNARE Proteins. Mol Biol Cell 1998 Sep;9(9):2423-37
isoprenylated v-SNARE protein, Xenopus  0   *Xenopus Proteins *R-SNARE Proteins. Biochem Biophys Res Commun 1998 Jul 20;2482):235-9
VAMP8 protein, human  0   *R-SNARE Proteins Nerve Tissue Proteins. Mol Biol Cell 1998 Jun;9(6):1549-63
tomosyn protein, mouse  0   *Nerve Tissue Proteins *R-SNARE Proteins. Neuron 1998 May;20(5):905-15
YKT6 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *R-SNARE Proteins. J Biol Chem 1997 Jul 11;272(28):17776-83
Sec22 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *R-SNARE Proteins. Mol Cell Biol 1991 Feb;11(2):872-85
ERS-24 protein, Cricetulus griseus  0   *R-SNARE Proteins Endoplasmic Reticulum. J Cell Biol 1997 Jun 2;137(5):1017-28
SAR1 protein, Arabidopsis  0   *Arabidopsis Proteins *R-SNARE Proteins. Nat Genet 1996 Jun;13(2):227-9
sec22 homolog protein, rat  0   *R-SNARE Proteins. J Biol Chem 1996 Mar 8;271(10):5671-9
synaptobrevin protein, Drosophila  0   *Drosophila Proteins *R-SNARE Proteins. Neuron 1995 Feb;14(2):341-51
n-synaptobrevin protein, Drosophila  0   *Drosophila Proteins *R-SNARE Proteins. J Neurosci 1993 Nov;13(11):4924-35
SNC2 protein, S cerevisiae  0   *R-SNARE Proteins *Saccharomyces cerevisiae Proteins. Cell 1993 Sep 10;74(5):855-61
SNC1 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *R-SNARE Proteins. Cell 1993 Sep 10;74(5):855-61

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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