Angiotensin II Type 1 Receptor Blockers (definition)

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ψ	Angiotensin II Type 1 Receptor Blockers

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Definition: Agents that antagonize ANGIOTENSIN II TYPE 1 RECEPTOR. Included are ANGIOTENSIN II analogs such as SARALASIN and biphenylimidazoles such as LOSARTAN. Some are used as ANTIHYPERTENSIVE AGENTS.

See Also Angiotensin-Converting Enzyme Inhibitors

Other names Type 1 Angiotensin Receptor Blockers; Type 1 Angiotensin Receptor Antagonists; Selective Angiotensin II Receptor Antagonists; Sartans; Angiotensin II Type 1 Receptor Antagonists

Substances having this pharmacologic action: Saralasin; 1-Sarcosine-8-Isoleucine Angiotensin II; Losartan; enoltasosartan; telmisartan, hydrochlorothiazide drug combination; olmesartan; ZD 7155; olmesartan medoxomil; candesartan cilexetil; A 81988; irbesartan; valsartan; candesartan; Abbott 81282; telmisartan; tasosartan; saprisartan potassium

Substance	CAS Registry & name	Categories	Source	Drugs*
3-(5-(2-(1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-2-ethyl-5-isobutyl-7-methyl-3H-imidazo(4,5-b)pyridine	0	Imidazoles Pyridines Angiotensin II Type 1 Receptor Blockers PPAR gamma/agonists.	J Med Chem 2011 Jun 23;54(12):4219-33
azilsartan medoxomil	0	Benzimidazoles Oxadiazoles Angiotensin II Type 1 Receptor Blockers.	Hypertension 2011 Mar;57(3):413-20
telmisartan amlodipine combination	0	Benzimidazoles Benzoates *Amlodipine Drug Combinations Hypertension/drug therapy Angiotensin II Type 1 Receptor Blockers.	JAAPA. 2010 Jan;23(1):14	TWYNSTA
eprosartan mesylate dihydrate	0	Imidazoles Thiophenes Angiotensin II Type 1 Receptor Blockers.	J Pharm Sci 1999 Oct;88(10):1021-9	TEVETEN HCT
embusartan	156001-18-2	Dihydropyridines Tetrazoles Receptor, Angiotensin, Type 1/antagonists & inhibitors Angiotensin II Type 1 Receptor Blockers.	Arzneimittelforschung 1997 Sep;47(9):1016-23
fonsartan	0 2-butyl-4-(methylthio)-1-((2'-((((propylamino)carbonyl)amino)sulfonyl)(1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-carboxylic acid dipotassium salt	Biphenyl Compounds Imidazoles Angiotensin II Type 1 Receptor Blockers.	J Med Chem 1995 Jun 23;38(13):2357-77
forasartan	145216-43-9 Pyridine, 5-((3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl)-2-(2-(1H-tetrazol-5-yl)phenyl)	Pyridines Tetrazoles Angiotensin II Type 1 Receptor Blockers.	J Cardiovasc Pharmacol 1993 Oct;22(4):617-25

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

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