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Tripterygium

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Definition: A plant genus of the family CELASTRACEAE that is a source of triterpenoids and diterpene epoxides such as triptolide.  coordinate with specific PLANT STRUCTURES term if pertinent; for use in therapy coordinate IM with PHYTOTHERAPY (IM) + disease/drug ther (IM) + PLANT PREPARATIONS or its indentations/ther use (IM or NIM) + specific plant chemical /ther use (IM) if pertin    Other names wilfordius, Tripterygium; wilfordii, Tripterygium; hypoglaucums, Tripterygium; hypoglaucum, Tripterygium; Vines, Thundergod; Vine, Thundergod; Tripterygiums; Tripterygium wilfordius; Tripterygium hypoglaucums; Thundergod Vines; Tengs, Leigong; Teng, Leigong; Leigong Tengs; Tripterygium hypoglaucum; Thundergod Vine; Leigong Teng; Tripterygium wilfordii
 
SubstanceCAS Registry & nameCategoriesSource
triptoquinone A  142950-86-5   *Diterpenes Tripterygium. Biochem Biophys Res Commun 1996 Jul 16;224(2):579-85
tripchlorolide  132368-08-2 Bisoxireno(4b,5:8a,9)phenanthro(1,2-c)furan-4(2H)-one, 11-chloro-1b,3,6,6b,7,7a,9,10,11,11a-decahydro-9,10-dihydroxy-1b-methyl-10-(1-methylethyl)-, (1bS-(1aR*,1balpha,6bbeta,7abeta,8aR*,9alpha,10beta,11alpha,11abeta))  *Diterpenes *Phenanthrenes Tripterygium. Chung Kuo I Hsueh Ko Hsueh Yuan Hsueh Pao 1990;12(3):157
tripterine  34157-83-0 3-hydroxy-24-nor-2-oxo-1(10),3,5,7-friedelatetraen-29-oic acid  *Triterpenes Tripterygium. Chung Kuo Yao Li Hsueh Pao 1986;7(1):85
triptolide  38748-32-2   *Diterpenes *Phenanthrenes Epoxy Compounds Anti-Inflammatory Agents, Non-Steroidal Tripterygium.
Pharma Action Antispermatogenic Agents ; Immunosuppressive Agents ; Antineoplastic Agents, Alkylating 		J Am Chem Soc 94(20):7194;1972; J Org Chem 42(15):2569;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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