Definition: A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms.
Don't confuse MAP Kinase 2 with MAP KINASE KINASES referred to as MAP2 Kinases
Other names Mitogen Activated Protein Kinase 2; Mitogen Activated Protein Kinase 1; MAPK2 Mitogen Activated Protein Kinase; MAPK1 Mitogen Activated Protein Kinase; MAP Kinase, p42; Extracellular Signal Regulated Kinase 2; p42(Mapk) Kinase; p42(Mapk); MAPK2 Mitogen-Activated Protein Kinase; MAPK1 Mitogen-Activated Protein Kinase; p42(Mitogen-Activated Protein Kinase); p42 MAPK; p42 MAP Kinase; Mitogen-Activated Protein Kinase 2; MAP Kinase 2; Extracellular Signal-Regulated Kinase 2
