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Cyclin A

More information in Books or onNLM PubMed
Definition: A cyclin subtype that has specificity for CDC2 PROTEIN KINASE and CYCLIN-DEPENDENT KINASE 2. It plays a role in progression of the CELL CYCLE through G1/S and G2/M phase transitions.     
Examples Cyclin A1; Cyclin A2 		Other names E1A p60; Cyclins, Type A; Cyclin, Type A; Adenovirus E1A Associated Protein p60; Type A Cyclins; Type A Cyclin; Adenovirus E1A-Associated Protein p60
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-(((1,2-dicyano-2-(((4-methoxyphenyl)methylene)amino)vinyl)amino)carbonyl)-4-methylbenzenesulfonamide  0   *Sulfonamides Cyclin A/antagonists & inhibitors Cyclin-Dependent Kinase 2/antagonists & inhibitors. Bioorg Med Chem 2010 Nov 1;18(21):7639-50
cyclin A1, Xenopus  0   *Cyclin A *Xenopus Proteins. Genes Dev 1994 Apr 15;8(8):926-38
cyclin A2 protein, Xenopus  0   *Cyclin A.
N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(4-(2-oxo-1-pyrrolidinyl)phenyl)propanamide  0   *Pyrazoles *Pyrrolidinones Cyclin A/antagonists & inhibitors. J Med Chem 2005 Apr 21;48(8):2944-56
N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(2-naphthyl)acetamide  0   *Acetamides *Pyrazoles Cyclin A/antagonists & inhibitors. J Med Chem 2004 Jun 17;47(13):3367-80
cyclin A3 protein, Bos taurus  0   *Cyclin A. Structure 1995 Nov 15;3(11):1235-47

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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