Definition: A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
/drug eff permitted
Other names Proendothelin 1 Precursor; Preproendothelin 1; Precursor, Proendothelin-1; Endothelin-1, Big; Endothelin 1; Big Endothelin 1; Proendothelin-1 Precursor; Proendothelin (1-38); Preproendothelin-1; Preproendothelin; Endothelin, Big; Endothelin Type 1; ET-1 (Endothelin-1); Big Endothelin-1; Big Endothelin