encyclopedia of medical concepts
ψ 
ψ 
ψ 

Hydroxymethylglutaryl-CoA Reductase Inhibitors

More information in Books or onNLM PubMed
Definition: Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.  X ref STATINS, HMG-COA: do not confuse with statin protein in SCR   
See Also Hydroxymethylglutaryl CoA Reductases 		Other names Statins, HMG CoA; Reductase Inhibitors, Hydroxymethylglutaryl-CoA; Reductase Inhibitors, HMG-CoA; Inhibitors, Hydroxymethylglutaryl-CoA Reductase; Inhibitors, Hydroxymethylglutaryl Coenzyme A; Inhibitors, Hydroxymethylglutaryl CoA; Inhibitors, HMG CoA Reductase; Hydroxymethylglutaryl-Coenzyme A Inhibitors; Hydroxymethylglutaryl-CoA Inhibitors; Hydroxymethylglutaryl CoA Reductase Inhibitors; HMG-CoA Statins; HMG CoA Reductase Inhibitors; Inhibitors, Hydroxymethylglutaryl-Coenzyme A; Inhibitors, Hydroxymethylglutaryl-CoA; Inhibitors, HMG-CoA Reductase; Statins, HMG-CoA; HMG-CoA Reductase Inhibitors
Substances having this pharmacologic action: Pravastatin; Meglutol; Simvastatin; Lovastatin; compactin; pitavastatin; red yeast rice; rosuvastatin; amlodipine, atorvastatin drug combination; cerivastatin; atorvastatin; fluvastatin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Tocomin  0   *Tocotrienols Hydroxymethylglutaryl-CoA Reductase Inhibitors. Phytother Res. 2011 Nov;25(11):1586-95
7-(4-((3-fluorobenzyl)carbamoyl)-5-cyclopropyl-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoic acid  0   *Heptanoic Acids *Imidazoles Hydroxymethylglutaryl-CoA Reductase Inhibitors. Bioorg Med Chem Lett 2011 May 1;21(9):2725-31
coenzyme Q10  303-98-0   Ubiquinone/*analogs & derivatives Hydroxymethylglutaryl-CoA Reductase Inhibitors Electron Transport Chain Complex Proteins.
Pharma Action Vitamins 		Biochem Biophys Res Commun 1980;93(2):409; Biochim Biophys Acta 462:501;1977; Biokhimiia 1979;44(10):1884; J Biol Chem 1980;255(8):3278

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy