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Insulin-Like Growth Factor Binding Proteins

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Definition: A family of soluble proteins that bind insulin-like growth factors and modulate their biological actions at the cellular level. (Int J Gynaecol Obstet 1992;39(1):3-9)  GEN or unspecified; prefer specifics; /biosyn /drug eff /physiol /ultrastruct permitted; DF: note short X refs   
Examples Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Protein 5; Insulin-Like Growth Factor Binding Protein 6 		Other names Somatomedin Binding Proteins; IGF Binding Proteins; Somatomedin-Binding Proteins; IGFBP; IGF-Binding Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
acid-labile subunit, Drosophila  0   *Insulin-Like Growth Factor Binding Proteins *Drosophila Proteins. Cell Metab 2008 Apr;7(4):333-8
IGFBPL1 protein, human  0   *Insulin-Like Growth Factor Binding Proteins *Tumor Suppressor Proteins. Biochem Biophys Res Commun 2005 May 27;331(1):261-6
Bono1 protein, mouse  0   *Insulin-Like Growth Factor Binding Proteins. Gene Expr Patterns 2004 Sep;4(5):595-9
insulin-like growth factor binding protein-related protein 1  0   *Insulin-Like Growth Factor Binding Proteins. Proc Natl Acad Sci U S A 1995 May 9;92(10):4472-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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