Definition: One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.
/biosyn /drug eff /physiol /ultrastruct permitted; DF: note short X refs
Other names Insulin Like Growth Factor Binding Protein 4; IGF Binding Protein 4; IGFBP-4; IGF-Binding Protein 4