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Bone Substitutes

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Definition: Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapatite, beta-tricalcium phosphate, and various other biomaterials. The bone substitutes as inert materials can be incorporated into surrounding tissue or gradually replaced by original tissue.  IM; coord with specific bone (IM) if relevant + substitute material (IM) if significant    Other names Materials, Bone Replacement; Material, Bone Replacement; Substitutes, Bone; Replacement Materials, Bone; Substitute, Bone; Replacement Material, Bone; Bone Substitute; Bone Replacement Material; Bone Replacement Materials
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
hydroxyapatite-ethyl vinyl acetate  0   *Hydroxyapatites *Vinyl Compounds Bone Substitutes. Toxicol Mech Methods. 2011 Sep;21(7):561-6.
hydroxyapatite-bioglass  0   *Ceramics *Hydroxyapatites Bone Substitutes. Toxicol Mech Methods. 2011 Sep;21(7):561-6.
Stimulan  0   *Calcium Sulfate Bone Substitutes. J Craniofac Surg. 2011 May;22(3):854-7
JECTOS  0   *Calcium Phosphates Bone Substitutes. Orthop Traumatol Surg Res 2010 Sep;96(5):574-8
TricOs T  0   *Calcium Phosphates *Bone Substitutes. Clin Oral Implants Res. 2009 Dec;20(12):1367-74
InterGro DBM putty  0   *Bone Substitutes. J Bone Joint Surg Am 2010 Feb;92(2):427-35
NanoBone  0   *Silicon Dioxide *Durapatite Drug Combinations Bone Substitutes. Clin Oral Implants Res 2008 Oct;19(10):1016-26
actifuse synthetic bone graft  0   *Calcium Phosphates *Silicates Bone Substitutes. Neurosurg Focus 2006;21(6):E9
Vitoss  0   *Calcium Phosphates *Silicates Bone Substitutes. J Biomed Mater Res B Appl Biomater 2004 Jul 15;70B(1):1-20
Calcigen S  0   *Bone Substitutes. J Craniofac Surg 2004 Sep;15(5):752-7
Colloss  0   *Bone Substitutes. Clin Oral Implants Res 2004 Apr;15(2):187-93
HE 800, Vibrio diabolicus  0   *Polysaccharides, Bacterial Bone Substitutes. Calcif Tissue Int 2003 Sep;73(3):232-6
Algipore  0   *Bone Substitutes. Clin Oral Implants Res. 2004 Feb;15(1):96-100
Novabone-C-M  0   *Silicones *Bone Substitutes. Ophthal Plast Reconstr Surg 2003 Nov;19(6):455-65
Capset  0   *Calcium Sulfate Bone Substitutes. Dent Implantol Update 2003 Jan;14(1):[Interview] (1-8)
HTR bioplant  0   *Polymers Bone Substitutes. J Long Term Eff Med Implants 1999;9(3):223-33
PepGen P-15  0   *Bone Substitutes. J Am Dent Assoc 1999 Dec;130(12):1698
coralline hydroxyapatite  0   *Ceramics *Hydroxyapatites Bone Substitutes. Pediatr Neurosurg 1998 Dec;29(6):324-7
OsteoGraf-N  0   *Bone Substitutes Bone Matrix Bone Transplantation. Int J Periodontics Restorative Dent 1998 Dec;18(6):528-43
endobon  158623-13-3   *Bone Substitutes. J Craniomaxillofac Surg 1996 Oct;24(5):300-4
Bio-Oss  0   *Minerals Bone Matrix Bone Substitutes. J Craniofac Sur 1992 Jul;3(1):25-9
HTR composite  26355-01-1 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, polymer with methyl 2-methyl-2-propenoate  *Methylmethacrylates *Polyhydroxyethyl Methacrylate Composite Resins Bone Substitutes Prostheses and Implants.
Pharma Action Biocompatible Materials 		NY J Dent 1983;53(8):387
calcium silicate  1344-95-2   *Calcium Compounds *Silicates Bone Substitutes. Environ Res 1981;26(1):51
Bioglass  0   *Ceramics Bone Cements Bone Substitutes.
Pharma Action Biocompatible Materials 		Am J Orthod 76(6):618;1979; J Biomed Mater Res 1980;14(1):23; J Biomed Mater Res 1980;14(1):55
octacalcium phosphate  13767-12-9 phosphoric acid, calcium salt (3:4)  *Calcium Phosphates Bone Substitutes. Can J Surg 22(6):527;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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