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Nicotinic Agonists

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Definition: Drugs that bind to and activate nicotinic cholinergic receptors (RECEPTORS, NICOTINIC). Nicotinic agonists act at postganglionic nicotinic receptors, at neuroeffector junctions in the peripheral nervous system, and at nicotinic receptors in the central nervous system. Agents that function as neuromuscular depolarizing blocking agents are included here because they activate nicotinic receptors, although they are used clinically to block nicotinic transmission.  GEN or unspecified; prefer specifics; DF: NICOTINIC AGON or NICOTINIC AG    Other names Nicotinic Cholinergic Agonists; Nicotinic Cholinergic Agonist; Agonists, Nicotinic Cholinergic; Agonists, Nicotinic; Agonist, Nicotinic Cholinergic; Agonist, Nicotinic; Nicotinic Agonist; Cholinergic Agonist, Nicotinic; Cholinergic Agonists, Nicotinic
Substances having this pharmacologic action: Lobeline; Nicotine; (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Dimethylphenylpiperazinium Iodide; varenicline; epibatidine; 3-(2,4-dimethoxybenzylidene)anabaseine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(5-chloropyridin-3-yl)-(1,4)diazepane  0   *Azepines *Pyridines Nicotinic Agonists. J Psychopharmacol. 2011 Oct;25(10):1347-56.
3-(3-(pyridine-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile  0   *Oxadiazoles *Pyridines Nicotinic Agonists. Biochem Pharmacol 2011 Oct 15;82(8):967-76

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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