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Skin, Artificial

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Definition: Synthetic material used for the treatment of burns and other conditions involving large-scale loss of skin. It often consists of an outer (epidermal) layer of silicone and an inner (dermal) layer of collagen and chondroitin 6-sulfate. The dermal layer elicits new growth and vascular invasion and the outer layer is later removed and replaced by a graft.  to stimulate new skin growth before replacement by graft    Other names Skin Substitutes; Artificial Skin; Substitutes, Skin; Substitute, Skin; Skins, Artificial; Skin Substitute; Artificial Skins
 
SubstanceCAS Registry & nameCategoriesSource
NovoSorb  0   *Polyurethanes Biocompatible Materials Skin, Artificial. J Burn Care Res. 2009 Jul-Aug;30(4):717-28
matriderm  0   *Collagen *Elastin Skin, Artificial. Exp Toxicol Pathol 2006 Mar;57(4):197-200
Alloderm  0   *Collagen Biocompatible Materials Skin, Artificial. Dent Implantol Update 2001 Sep;12(9):65-71
Apligraf  0   *Collagen Skin, Artificial. Int J Clin Pract 1998 Sep;52(6):408-13
integra artificial skin  0   *Chondroitin Sulfates *Collagen Skin, Artificial. J Burn Care Rehabil 1998 Jul-Aug;19(4):324-9

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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