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Cyclosporine

More information in Books or onNLM PubMed
Definition: A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).  a specific drug: do not confuse this or X ref with CYCLOSPORINS   
Pharmacological Action Antifungal Agents; Antirheumatic Agents; Dermatologic Agents; Enzyme Inhibitors; Immunosuppressive Agents 		Other names Cyclosporin A; OL 27400; OL 27 400; Neoral, Sandimmun; CyA NOF; CsANeoral; CsA Neoral; Sandimmune; Sandimmun Neoral; Sandimmun; Restasis; OL 27-400; Neoral; Cyclosporine A; Cyclosporin; CyA-NOF; CsA-Neoral; CiclosporinDrugs* : RESTASIS; SANGCYA; NEORAL; GENGRAF; CYCLOSPORINE; SANDIMMUNE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Iminoral  0   *Cyclosporine. Transplant Proc 2007 May;39(4):1214-8
DEBIO-025  0   *Cyclosporine. Hepatology 2006 Apr;43(4):761-70
MeAla(3)EtVal(4)-cyclosporin  0   *Cyclosporine. J Bioenerg Biomembr 2004 Aug;36(4):407-13
cyclosporin 29  0   *Cyclosporine. Cardiovasc Res 2004 Jan 1;61(1):115-22
voclosporin  0   *Cyclosporine. J Heart Lung Transplant 2003 Dec;22(12):1343-52
M1 cyclosporin metabolite  0   *Cyclosporine. J Chromatogr B Biomed Appl 1997 Mar 7;690(1-2):367-72
SDZ 211-811  0   *Cyclosporine. Proc Natl Acad Sci U S A 1997 May 13;94(10):5432-7
N-methyl-valyl-4-cyclosporin A  159605-70-6   *Cyclosporine. FEBS Lett 1996 Apr 8;384(1):53-7
AM 19  0   *Cyclosporine. Ther Drug Monit 1995 Oct;17(5):479-86
(5-hydroxynorvaline)-2-cyclosporin  0   *Cyclosporine. J Med Chem 1995 Aug 18;38(17):3361-7
(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine  0   *Cyclosporine. Am J Physiol 1995 Jan;268(1 Pt 2):F46-52
(melle-4)cyclosporin  143205-42-9 Cyclosporin A, 9-(N-methyl-L-isoleucine)  *Cyclosporine. Nature 1994 Nov 24;372(6504):363-5
FR 901459  153049-50-4 Cyclosporin A, 4-L-leucine-7-L-threonine-10-L-leucine  *Cyclosporine. J Antibiot (Tokyo) 1993 Dec;46(12):1788-98
cyclosporin H  83602-39-5   *Cyclosporine. Science 1986;234(4772):68
cyclosporin G  74436-00-3   *Cyclosporine.
Pharma Action Immunosuppressive Agents 		Lancet 1985;1(8441):1342

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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