encyclopedia of medical concepts
ψ
ψ
ψ
ψ
Factor VIIa
More information
in Books
or on
Definition
: Activated form of factor VII. Factor VIIa activates factor X in the extrinsic pathway of blood coagulation.
a blood coag factor; a serine proteinase; /defic
See Also
Coagulants
Other names
VIIa, Coagulation Factor; Factor VIIa, Coagulation; Blood Coagulation Factor VII, Activated; Factor VII, Activated; Coagulation Factor VIIa; Activated Factor VII
Substance
CAS Registry & name
Categories
Source
Drugs
*
MC 710
0
*Factor X
*Factor VIIa
Drug Combinations.
Thromb Res. 2012 Jan;129(1):62-7.
benzyloxycarbonyl-
phenylalanyl-
phenylalanyl-
arginine benzyl ketone
0
*Oligopeptides
Factor VIIa/antagonists & inhibitors.
Bioorg Med Chem Lett 2011 Jul 1;21(13):3918-22
BMS 593214
0
*Heterocyclic Compounds with 4 or More Rings
*Benzoic Acids
Factor VIIa/antagonists & inhibitors.
Thromb Haemost 2010 Aug 2;104(2):261-9
glycoPEGylated factor VIIa
0
*Factor VIIa.
Thromb Haemost 2008 Nov;100(5):920-8
4-
(2-
(3-
aminobenzenesulfonylamino)-
1-
(3,5-
diethoxy-
2-
fluorophenyl)-
2-
oxoethylamino)-
2-
hydroxybenzamidine
0
*Benzamidines
*Sulfonamides
Factor VIIa/antagonists & inhibitors.
J Biol Chem 2005 Mar 11;280(10):9160-9
propylsulfonamide-
threonyl-
methionyl-
4-
aminobenzamidine
0
*Benzamidines
*Dipeptides
Factor VIIa/antagonists & inhibitors.
Biochem Biophys Res Commun 2004 Nov 26;324(4):1227-33
N-
(4-
(amino(imino)methyl)benzyl)-
2-
(6-
(3,5-
diaminophenyl)-
3-
(isopropylamino)-
2-
oxopyridin-
1(2H)-
yl)acetamide
0
*Acetamides
*Pyridones
Factor VIIa/antagonists & inhibitors.
J Med Chem 2003 Oct 23;46(22):4696-701
3-
amino-
5-
(1-
(2-
((4-
(amino(imino)methyl)benzyl)amino)-
2-
oxoethyl)-
5-
(isopropylamino)-
6-
oxo-
1,6-
dihydropyridin-
2-
yl)benzoic acid
0
*Pyridones
*Benzoic Acids
Factor VIIa/antagonists & inhibitors.
J Med Chem 2003 Oct 23;46(22):4696-701
3-
amino-
5-
(1-
(2-
((4-
(amino(imino)methyl)benzyl)amino)-
2-
oxoethyl)-
3-
chloro-
5-
(isopropylamino)-
6-
oxo-
1,6-
dihydropyrazin-
2-
yl)benzoic acid
0
*Aminobenzoic Acids
*Pyrazines
Thromboplastin/antagonists & inhibitors
Factor VIIa/antagonists & inhibitors.
J Pharmacol Exp Ther 2003 Sep;306(3):1115-21
5-
(5-
amidinoindol-
2-
yl)-
6-
hydroxy-
3-
((3-
nitrophenyl)phenyl)acetic acid
0
*Amidines
*Phenylacetates
Thromboplastin/antagonists & inhibitors
Factor VIIa/antagonists & inhibitors.
Bioorg Med Chem Lett 2001 Sep 3;11(17):2253-6
phenylalanyl-
phenylalanyl-
arginyl-
recombinant FVIIa
0
*Factor VIIa
Recombinant Proteins.
J Vasc Surg 2001 May;33(5):1072-9
dansyl-
glutamyl-
glycyl-
arginyl-
factor VIIa
0
*Dansyl Compounds
*Factor VIIa
Recombinant Fusion Proteins.
Arterioscler Thromb Vasc Biol 1997 Nov;17(11):3049-56
recombinant FVIIa
0
*Factor VIIa
Recombinant Proteins.
Baillieres Clin Haematol 1996 Jun;9(2):291-303
des(1-
44) factor VIIa
0
*Peptide Fragments
*Factor VIIa.
FEBS Lett 1994 Jun 20;347(1):73-9
des(1-
38) factor VIIa
0
*Factor VIIa
*Peptide Fragments.
FEBS Lett 1992 Jul 20;306(2-3):265-8
tissue-
factor-
pathway inhibitor 2
0
*Glycoproteins
Lipoproteins
Factor VIIa/antagonists & inhibitors.
Pharma Action
Serine Proteinase Inhibitors
Biochim Biophys Acta 2003;1621(3):242; Br J Obstet Gynaecol 1979;86(11):888-93; Br J Obstet Gynaecol 1979;86(8):642; Clin Chim Acta 1979; 95(3):509