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Imipenem

More information in Books or onNLM PubMed
Definition: Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.     
Pharmacological Action Anti-Bacterial Agents
Other names N-Formimidoylthienamycin; Imipemide; N Formimidoylthienamycin; MK 0787; Anhydrous Imipenem; MK0787; MK-0787; Imipenem, Anhydrous
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
xanthoradone C  0   Imipenem/*analogs & derivatives. J Antibiot (Tokyo). 2010 Jun;63(6):329-30
xanthoradone B  0   Imipenem/*analogs & derivatives. J Antibiot (Tokyo). 2009 Aug;62(8):431-4
xanthoradone A  0   Imipenem/*analogs & derivatives. J Antibiot (Tokyo). 2009 Aug;62(8):431-4
29-kDa outer membrane protein, Acinetobacter baumannii  0   *Bacterial Proteins Acinetobacter Infections Imipenem Drug Resistance, Multiple, Bacterial. J Clin Microbiol 2002 Dec;40(12);4776-8
cilastatin, imipenem drug combination  92309-29-0   *Imipenem *Cilastatin Drug Combinations. J Antimicrob Chemother 1985;15(2):233PRIMAXIN; IMIPENEM AND CILASTATIN

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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