encyclopedia of medical concepts
ψ 
ψ 
ψ 

Deoxyribonucleases, Type II Site-Specific

More information in Books or onNLM PubMed
Definition: Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.4.  a DNA restriction enzyme; DF: DNASE SS II   
Examples Deoxyribonuclease BamHI; Deoxyribonuclease EcoRI; Deoxyribonuclease HindIII; Deoxyribonuclease HpaII 		Other names Type II Restriction Enzymes; Restriction Endonucleases, Type II; DNase, Site-Specific, Type II; DNA Restriction Enzymes, Type II; Site Specific DNase, Type II; Deoxyribonucleases, Type II Site Specific; Type II Site-Specific Deoxyribonucleases; Type II Site-Specific DNase; Type II Site Specific Deoxyribonucleases; Type II Site Specific DNase; Site-Specific DNase, Type II; Deoxyribonucleases, Type II, Site-Specific; Deoxyribonucleases, Type II, Site Specific; DNase, Site Specific, Type II
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
sfaAI endonuclease, Yersinia enterocolitica  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Med Dosw Mikrobiol. 2009;61(2)133-42
HO protein, S cerevisiae  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific *Saccharomyces cerevisiae Proteins.
BsaI endonuclease  EC 3.1.21.4   *Deoxyribonucleases, Type II Site-Specific. J Mol Biol. 2004 Mar 26;337(3):573-83
endodeoxyribonuclease BsmBI  EC 3.1.21.4   *Deoxyribonucleases, Type II Site-Specific. J Mol Biol. 2004 Mar 26;337(3):573-83
DNA restriction enzyme EcoT38I, E coli  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific *Escherichia coli Proteins. J Bacteriol 2003 Apr;185(7):2296-305
HrgA protein, Helicobacter pylori  EC 3.1.21.4   *Deoxyribonucleases, Type II Site-Specific. J Bacteriol 2003 Jan;185(1):295-301
endodeoxyribonuclease FspAI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 2001 Dec 15;29(24):E120
endodeoxyribonuclease TauI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. FEMS Microbiol Lett 2001 Nov 13;204(2):253-7
endodeoxyribonuclease TatI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. FEMS Microbiol Lett 2001 Nov 13;204(2):253-7
endodeoxyribonuclease BstNBI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 2001 Jun 15;29(12):2492-501
endodeoxyribonuclease CfrBI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res. 2000 Oct 1;28(19):3817-22
NgoMIV endonuclease  EC 3.1.21.4   *Deoxyribonucleases, Type II Site-Specific. Nat Struct Biol. 2000 Sep;7(9):705-7
endodeoxyribonuclease BtrI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res. 2000 28: e56
endodeoxyribonuclease Hpy188I  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific.
endodeoxyribonuclease BslI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. J Bacteriol 2000 Feb;182(4):949-55
endodeoxyribonuclease HaeIV  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. J Mol Biol 1999 Nov 12;293(5):1055-65
endodeoxyribonuclease HpyBII  EC 3.2.21.-   *Deoxyribonucleases, Type II Site-Specific. FEMS Microbiol Lett 1999 Oct 1;179(1):175-80
endodeoxyribonuclease BseSI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1999 Jul 1;27(13):2644-5
endodeoxyribonuclease PsiI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Biochemistry (Mosc) 1999 Apr;64(4):481-2
endodeoxyribonuclease AbeI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1998 Nov 1;26(21):4917-8
endodeoxyribonuclease Ecl18kI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. FEBS Lett 1998 Aug 21;433(3):233-6
endodeoxyribonuclease HgaI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Prenat Diagn 1998 Jun;18(6):629-31
endodeoxyribonuclease BfiI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1998 Jul 15;26(14):3348-9
endodeoxyribonuclease LlaDII  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Appl Environ Microbiol 1998 Jul;64(7):2424-31
endodeoxyribonuclease SceIV  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Biochem Biophys Res Commun 1998 Jul 9;248(1):127-33
endodeoxyribonuclease BecAI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Mol Gen Mikrobiol Virusol 1998;(2):35-8
endodeoxyribonuclease UnbI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Acta Biochim Pol 1997;44(4):849-52
CCGCTC-specific type II deoxyribonucleases  EC 3.1.21.4   *Deoxyribonucleases, Type II Site-Specific. Prikl Biokhim Mikrobiol 1997 Sep-Oct;33(5):556-8
endodeoxyribonuclease BplI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1997 Nov 15;25(22):4444-6
splase  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific *Sp1 Transcription Factor. J Protein Chem 1996 Jul;15(5):481-9
endodeoxyribonuclease BccI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Gene 1996 Nov 14;179(2):245-9
endodeoxyribonuclease BaeI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1996 Sep 15;24(18):3590-2
endodeoxyribonuclease SapI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Methods Mol Biol 1996;57:297-310
endodeoxyribonuclease BsgI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Biotechniques 1996 Mar;20(3):446-51
endodeoxyribonuclease Taq52 I  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1995 Nov 25;23(22):4573-5
endodeoxyribonuclease SimI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1995 Jul 25;23(14):2571-2
endodeoxyribonuclease SgfI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Gene 1995 Jul 4;160(1):55-8
endodeoxyribonuclease Sse1825I  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Gene 1995 May 19;157(1-2):311-4
endodeoxyribonuclease MmeII  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Gene 1995 May 19;157(1-2):87-92
endodeoxyribonuclease Sse8647I  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1995 Mar 11;23(5):742-4
SanDI endonuclease  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Gene 1995 Mar 21;155(1):129-30
endodeoxyribonuclease AflIII  EC 3.1.21.4   *Deoxyribonucleases, Type II Site-Specific. Hum Genet 1995 Mar;95(3):363-4
SegA protein, Enterobacteria phage T4  EC 3.1.21.-   *Viral Proteins *Deoxyribonucleases, Type II Site-Specific. J Bacteriol 1994 Nov;176(21):6439-48
endodeoxyribonuclease CviRI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1994 Sep 25;22(19):3928-9
endodeoxyribonuclease Csp68KI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. J Bacteriol 1994 Sep;176(17):5565-70
endodeoxyribonuclease SfcI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Gene 1993 Dec 22;136(1-2):371-2
endodeoxyribonuclease XcmI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Gene 1993 Oct 29;133(1):85-9
Tsp45I endonuclease, Thermus sp. YS45  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1993 Sep 11;21(18):4397
endodeoxyribonuclease TspEI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Gene 1993 Sep 6;131(1):83-6
endodeoxyribonuclease BseRI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1993 Jul 25;21(15):3585
endodeoxyribonuclease Bsp1407I  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1993 May 25;21(10):2514
endodeoxyribonuclease BspLU11I  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1993 Mar 25;21(6):1495
GCANNNNNTGC -specific type II deoxyribonucleases  EC 3.1.21.4   *Deoxyribonucleases, Type II Site-Specific. Biochim Biophys Acta 1993 Mar 26;1162(3):323-5
endodeoxyribonuclease PmeI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. J Bacteriol 1992 Dec;174(23):7770-7
endodeoxyribonuclease SrfI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. J Bacteriol 1992 Dec;174(23):7566-71
endodeoxyribonuclease AscI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. J Bacteriol 1992 Dec;174(23):7566-71
endodeoxyribonuclease VpaK32I  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Gene 1992 Aug 1;117(1):103-6
WCCGGW-specific type II deoxyribonucleases  EC 3.1.21.4   *Deoxyribonucleases, Type II Site-Specific. Gene 1992 Aug 1; 117(1):99-101
endodeoxyribonuclease FsiI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1992 Jul 25;20(14):3789
endodeoxyribonuclease AclI  EC 3.1.21.-   *Deoxyribonucleases, Type II Site-Specific. Nucleic Acids Res 1992 Jul 25;20(14):3787
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy