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Tromethamine

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Definition: An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)     
Pharmacological Action Buffers; Excipients 		Other names Trometamol; Trisamine; Tris Buffer; Trometamol Abbott Brand; Trizma; Tris-Mg(II)-KCl Buffer; Tris-Magnesium(II)-Potassium Chloride Buffer; Tris(hydroxymethyl)aminomethane; Tri(hydroxymethyl)aminomethane; Abbott Brand of Trometamol; ThamDrugs* : THAM-E; THAM
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
dexlipotam  0   *Thioctic Acid *Tromethamine Drug Combinations. Int J Clin Pharmacol Ther 2007 Jul;45(7):385-93
LST buffer  0   *Polysorbates *Tromethamine Buffers Tissue Preservation. Am J Clin Pathol 1999 Jun;111(6):748-52
dexketoprofen trometamol  0   Ketoprofen/*analogs & derivatives Tromethamine/*analogs & derivatives.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal 		J Clin Pharmacol 1998 Dec;38(12 Suppl):1-2S
Tribonate  133249-32-8   *Bicarbonates *Tromethamine Buffers. Resuscitation 1994 Jul;28(1):27-36
Laemmli buffer  0   *Sodium Dodecyl Sulfate *Tromethamine. Anal Biochem 1994 May 15;219(1):144-6
TES-Tris yolk buffer  0   *Glucose *Tromethamine Buffers Egg Yolk Semen Preservation. Microsc Electron Biol Celular 1991 Jun;15(1):107-18
Krebs-Henseleit solution  0   Glucose Tromethamine Cardioplegic Solutions Organ Preservation Solutions. Can J Surg 1992 Apr;35(2):165-8
Tris-borate-EDTA buffer  0   *Boric Acids *Edetic Acid *Tromethamine Buffers. Biotechniques 991;10(2):182
1,2-dioleoyl-sn-glycero-3-phospho-tris  131235-28-4   *Glycerophospholipids Tromethamine/*analogs & derivatives. Biochemistry 1991;30(7):1746
BF5 diluent  0   *Dibekacin *Sulfonic Acids *Tromethamine. Lab Anim 1990;24(2):172
pyridoxal phosphate, trisodium citrate, tromethamine drug combination  0   *Citrates *Pyridoxal Phosphate *Tromethamine Drug Combinations. Haematologica 1990;75(1):38
carboprost tromethamine  58551-69-2   *Carboprost *Tromethamine Drug Combinations.
Pharma Action Oxytocics 		Am J Obstet Gynecol 1990;162(1):205HEMABATE
Trisdine  123354-94-9   *Edetic Acid *Tromethamine Chlorhexidine/*analogs & derivatives Drug Combinations. Br J Urol 1988;62(2):140
tromethamine tiaprofenate  62715-04-2   *Propionic Acids *Tromethamine Drug Combinations. Minerva Anestesiol 1987;53(10):587
2-(hydroxymethyl)-2-nitro-1,3-propanediol  126-11-4   Tromethamine/*analogs & derivatives. Arch Dermatol 1982;118(12):997
1,3-bis(tris(hydroxymethyl)methylamino)propane  64431-96-5 1,3-Propanediol, 2,2'-(1,3-propanediyldiimino)bis(2-(hydroxymethyl))  Tromethamine/*analogs & derivatives. J Gen Physiol 1982;79(4):529
tris-boric-polyol buffer  0   *Boric Acids *Polymers *Tromethamine Drug Combinations Buffers. Lab Delo 1981;(4):232
TEST mixture  77044-70-3 Ethanesulfonic acid, 2-((2-hydroxy-1,1-bis(hydroxymethyl)ethyl)amino)-, mixt. with 2-amino-2-(hydroxymethyl)-1,3-propanediol  *Tromethamine Drug Combinations. Cryobiology 1980;17(5):458
Bistris  6976-37-0   Tromethamine/*analogs & derivatives Buffers. Eur J Biochem 1980;107(2):455
lodoxamide tromethamine  63610-09-3 2,2'-((2-chloro-5-cyano-1,3-phenylene)diimino)bis(2-oxoacetic acid), compd. with 2-amino-2- (hydroxymethyl)-1,3-propanediol (1:2)  Nitriles Oxamic Acid/*analogs & derivatives Tromethamine/*analogs & derivatives Antioxidants.
Pharma Action Histamine H1 Antagonists 		Int Arch Allergy Appl Immunol 56:416;1978; Monogr Allergy 14:299;1979ALOMIDE
aloglutamol  13755-41-4 tris(hydroxymethyl)aminomethanegluconate dihydroxyaluminate  *Aluminum Hydroxide Tromethamine/*analogs & derivatives. Panminerva Med 18(7-8):235;1976; Urol Internat 33(4):213;1978
TES  7365-44-8 N-tris(hydroxymethyl)methyl-2-aminomethane sulfonate  Tromethamine/*analogs & derivatives Buffers. Aust J Biol Sci 25(5):1047;1973

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