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Thioredoxin-Disulfide Reductase

More information in Books or onNLM PubMed
Definition: A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the presence of NADP+. It was formerly listed as EC 1.6.4.5  DF: THIOREDOXIN REDUCTASE   
Examples Thioredoxin Reductase 1; Thioredoxin Reductase 2 		Other names Thioredoxin Reductase (NADPH); Thioredoxin Disulfide Reductase; Reductase, Thioredoxin-Disulfide; Reductase, Thioredoxin; Reductase, NADPH-Thioredoxin; Reductase, NADP-Thioredoxin; NADPH Thioredoxin Reductase; NADP Thioredoxin Reductase; Thioredoxin Reductase; NADPH-Thioredoxin Reductase; NADP-Thioredoxin Reductase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bromo(1,3-diethyl-4,5-bis(2-fluorophenyl)-1,3-dihydro-2H-imidazol-2-ylidene)gold(I)  0   *Organogold Compounds Thioredoxin-Disulfide Reductase/antagonists & inhibitors. J Med Chem. 2011 Dec 22;54(24):8605-15.
bis(2-amino-5-methylthiazole)tetrachlororuthenate(III)  0   *Organometallic Compounds Ruthenium Thioredoxin-Disulfide Reductase/antagonists & inhibitors. J Med Chem 2007 Nov 29;50(24):5871-4
ANTR-C protein, Arabidopsis  EC 1.8.1.9   *Thioredoxin-Disulfide Reductase *Arabidopsis Proteins. Biochem Biophys Res Commun 2006 Sep 22;348(2):478-84
PX 916  0   *Dioxanes Glycine/*analogs & derivatives Thioredoxin-Disulfide Reductase/antagonists & inhibitors. Mol Cancer Ther 2006 Mar;5(3):630-6
TXNRD3NT1 protein, human  EC 1.6.4.5   *Thioredoxin-Disulfide Reductase. Mamm Genome 2005 Jan;16(1):41-9
TXNRD3 protein, human  EC 1.11.1.-   *Thioredoxin-Disulfide Reductase.
NTRB protein, Arabidopsis  EC 1.6.4.5   *Thioredoxin-Disulfide Reductase *Arabidopsis Proteins Mitochondrial Proteins. FEBS Lett 2005 Jan 17;579(2):337-42
NTRA protein, Arabidopsis  EC 1.6.4.5   *Thioredoxin-Disulfide Reductase *Arabidopsis Proteins. FEBS Lett 2005 Jan 17;579(2):337-42
TRR1 protein, Pneumocystis jirovecii  EC 1.6.4.5   *Thioredoxin-Disulfide Reductase. Gene 2003 May 22;310:175-83
TRR1 protein, Pneumocystis carinii  EC 1.6.4.5   *Fungal Proteins *Thioredoxin-Disulfide Reductase. Gene 2003 May 22;310:175-83
thioredoxin-thioredoxin reductase hybrid protein, Mycobacterium leprae  0   *Bacterial Proteins *Thioredoxins *Thioredoxin-Disulfide Reductase. J Biol Chem 1995 Oct 27;270(43):25604-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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