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Strophanthidin

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Definition: 3 beta,5,14-Trihydroxy-19-oxo-5 beta-card-20(22)-enolide. The aglycone cardioactive agent isolated from Strophanthus Kombe, S. gratus and other species; it is a very toxic material formerly used as digitalis. Synonyms: Apocymarin; Corchorin; Cynotoxin; Corchorgenin.  a cardioactive agent    Other names Cymarigenin; Corchsularin; Convallatoxigenin; KStrophanthidin; K Strophanthidin; K-Strophanthidin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
technetium Tc 99m strophanthidin thiosemicarbazone  0   *Organotechnetium Compounds Strophanthidin/*analogs & derivatives. Int J Rad Appl Instrum (B) 1986;31(1):75
strophanthidin-3-tosyloxyacetate  78730-59-3 Card-20(22)-enolide, 5,14-dihydroxy-3-(((((4-methylphenyl)sulfonyl)oxy)acetyl)oxy)-19-oxo-, (3beta,5beta)  Strophanthidin/*analogs & derivatives. Br J Pharmacol 1981;72(1):25
strophanthidin 3-bromoacetate  4956-18-7   Strophanthidin/*analogs & derivatives. Basic Res Cardiol 1981;76(1):62
strophanthidin digitaloside  65681-32-5 Card-20(22)-enolide, 3-((6-deoxy-3-O-methyl-D-galactosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)  Strophanthidin/*analogs & derivatives Digitalis Glycosides. Arch Pharm (Weinheim) 310(11):905;1977
strophanthidin 6-deoxyglucoside  5822-57-1 Card-20(22)-enolide, 3-((6-deoxy-beta-D-gulopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)  Strophanthidin/*analogs & derivatives. Arch Pharm (Weinheim) 310(11):905;1977
strophanthidin arabinoside  28071-51-4   Strophanthidin/*analogs & derivatives. Farmakol Toksikol 40(6):703;1977
strophanthidin 3,5-bis-p-benzoyl benzoate  55601-19-9 Card-20(22)-enolide, 3,5-bis((4-benzoylbenzoyl)oxy)-14-hydroxy-19-oxo-, (3beta,5beta)  Strophanthidin/*analogs & derivatives. Res Commun Chem Pathol Pharmacol 10(4):605;1975
acetylstrophanthidin  60-38-8 3 beta,5,14,19-tetrahydroxy-5 beta-card-20(22)- enolide 19-acetate  Strophanthidin/*analogs & derivatives. Circ Res 41(5):622;1977; New Engl J Med 296(6):301;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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