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Saponins

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Definition: A type of glycoside widely distributed in plants. Each consists of a sapogenin as the aglycone moiety, and a sugar. The sapogenin may be a steroid or a triterpene and the sugar may be glucose, galactose, a pentose, or a methylpentose.     
Examples Escin; Ginsenosides; Holothurin; Solanine 		Other names Saponin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-O-beta-D-glucopyranosyl-(1-2)-beta-D-glucopyranosyl subprogenin D  0   *Saponins *Triterpenes. Molecules. 2012;17(1) (dup#13):295-302
mimengoside I  0   *Saponins *Triterpenes Neuroprotective Agents. J Asian Nat Prod Res. 2012;14(4):342-7
mimengoside H  0   *Saponins *Triterpenes Neuroprotective Agents. J Asian Nat Prod Res. 2012;14(4):342-7
3-O-D-xylopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-2)-beta-D-xylopyranosyl oleanolic acid 28-O-beta-D-glucopyranoside  0   *Saponins *Triterpenes Antineoplastic Agents, Phytogenic. J Asian Nat Prod Res. 2012;14(4):333-41
11alpha,12alpha-epoxy-3-O-beta-D-xylopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-2)-beta-D-xylopyranosyl-olean-28,13beta-olide  0   *Saponins *Triterpenes Antineoplastic Agents, Phytogenic. J Asian Nat Prod Res. 2012;14(4):333-41
11alpha,12alpha-epoxy-3-O-beta-D-xylopyranosyl-olean-28,13beta-olide  0   *Saponins *Triterpenes Antineoplastic Agents, Phytogenic. J Asian Nat Prod Res. 2012;14(4):333-41
3-O-beta-D-glucopyranosyl(1-4)-beta-D-fucopyranosyl-(22S,24Z)-cycloart-24-en-3beta,22,26,29-tetraol 26-O-beta-D-glucopyranoside  0   *Saponins *Triterpenes Antineoplastic Agents, Phytogenic. J Asian Nat Prod Res. 2012;14(4):327-32
3-O-beta-D-glucopyranosyl(1-4)-beta-D-fucopyranosyl-(22S,24Z)-cycloart-24-en-3beta,22,26,30-tetraol 26-O-beta-D-glucopyranoside  0   *Saponins *Triterpenes Antineoplastic Agents, Phytogenic. J Asian Nat Prod Res. 2012;14(4):327-32
pennogenin-3-O-beta-D-glucopyranosyl-(1-3)-(alpha-L-rhamnopyranosyl-(1-2))-beta-D-glucopyranoside  0   *Saponins. J Asian Nat Prod Res. 2012;14(4):314-21
ilekudinchoside G  0   *Saponins *Triterpenes. J Asian Nat Prod Res. 2012;14(4):308-13
ilekudinchoside F  0   *Saponins *Triterpenes. J Asian Nat Prod Res. 2012;14(4):308-13
(3beta,5alpha,6beta,25R)-6-((beta-D-glucopyranosyl)oxy)spirostan-3-yl O-beta-D-glucopyranosyl-(1-2)-O-(beta-D-glucopyranosyl-(1-3))beta-D-galactopyranoside  0   *Saponins *Spirostans. Fitoterapia. 2011 Dec;82(8):1175-80
dexyloprimulanin  0   *Saponins. Phytochemistry. 2011 Nov;72(16):2075-80
3-O-beta-D-glucopyranosyl-28-O-(beta-D-glucopyranosyl(1-2))-beta-D-glucopyranosyl-21beta,22alpha-dihydroxyl-olean-12-ene  0   *Saponins Oleanolic Acid/*analogs & derivatives. J Asian Nat Prod Res. 2012;14(3):216-23
3-O-beta-D-glucopyranosyl(1-6)-(angeloyl(1-2))-beta-D-glucopyranosyl-28-O-alpha-L-rhamnopyranosyl(1-2)-(beta-D-glucopyranosyl(1-6))-beta-D-glucopyranosyl-21beta,22alpha-dihydroxyl-olean-12-ene  0   *Saponins Oleanolic Acid/*analogs & derivatives. J Asian Nat Prod Res. 2012;14(3):216-23
acerboside B  0   *Saponins *Triterpenes. J Asian Nat Prod Res. 2012 Feb;14(2);135-40
acerboside A  0   *Saponins *Triterpenes. J Asian Nat Prod Res. 2012 Feb;14(2);135-40
3-O-(apifuranosyl-(1-3)-glucopyranosyl)oleanolic acid 28-O-apifuranosyl-(1-3)-xylopyranosyl-(1-4)-(rhamnopyranosyl-(1-3))-rhamnopyranosyl-(1-2)-xylopyranoside  0   *Saponins. Carbohydr Res. 2011 Dec 13;346(17):2699-704.
3-O-glucopyranosyloleanolic acid 28-O-xylopyranosyl-(1-4)-rhamnopyranosyl-(1-2)-xylopyranoside  0   *Saponins. Carbohydr Res. 2011 Dec 13;346(17):2699-704.
O-(3)-glucopyranosyl-(1-2)-arabinopyranosylpregn-5-en-3,20-diol  0   *Saponins. Arch Pharm Res. 2011 Aug;34(8):1297-300.
foenumoside B  0   *Saponins. Biochem Biophys Res Commun. 2012 Jan 13;417(2):800-6.
vaccaroside B  0   *Saponins Oleanolic Acid/*analogs & derivatives. Fitoterapia. 2011 Oct;82(7):1106-9
bifinoside A  0   *Saponins *Triterpenes. Chem Pharm Bull (Tokyo). 2011;59(11):1417-20
bifinoside B  0   *Saponins *Triterpenes. Chem Pharm Bull (Tokyo). 2011;59(11):1417-20
bifinoside C  0   *Saponins *Triterpenes. Chem Pharm Bull (Tokyo). 2011;59(11):1417-20
esculeoside B-5  0   *Saponins. Chem Pharm Bull (Tokyo). 2011;59(11):1403-5
esculeoside B-1  0   *Saponins. Chem Pharm Bull (Tokyo). 2011;59(11):1403-5
QB 90U  0   *Saponins Adjuvants, Immunologic. Vaccine. 2011 Nov 15;29(49):9183-93.
sarsasapogenyl glucopyranosyl-(1-4)-(glucopyranosyl-(1-6))glucopyranoside  0   *Saponins. Carbohydr Res. 2011 Nov 8;346(15):2406-13.
sarsasapogenyl arabinopyranosyl-(1-4)-(arabinopyranosyl-(1-6))glucopyranoside  0   *Saponins. Carbohydr Res. 2011 Nov 8;346(15):2406-13.
sarsasapogenyl glucopyranosyl-(1-4)-(arabinopyranosyl-(1-6))glucopyranoside  0   *Saponins. Carbohydr Res. 2011 Nov 8;346(15):2406-13.
bethoside B  0   *Phytosterols *Saponins. J Org Chem. 2011 Sep 2;76(17):7275-80
bethoside C  0   *Phytosterols *Saponins. J Org Chem. 2011 Sep 2;76(17):7275-80
mandshunoside B  0   *Saponins *Triterpenes. J Asian Nat Prod Res. 2011 Dec;13(12):1104-9
mandshunoside A  0   *Saponins *Triterpenes. J Asian Nat Prod Res. 2011 Dec;13(12):1104-9
mussaendoside T  0   *Saponins Oleanolic Acid/*analogs & derivatives. J Asian Nat Prod Res. 2011 Oct;13(11):1008-13
pallidifloside C  0   *Saponins *Steroids. J Asian Nat Prod Res. 2011 Oct;13(11):1014-22
pallidifloside B  0   *Saponins *Steroids. J Asian Nat Prod Res. 2011 Oct;13(11):1014-22
pallidifloside A  0   *Saponins *Steroids. J Asian Nat Prod Res. 2011 Oct;13(11):1014-22
clethroidoside H  0   *Saponins *Triterpenes. J Nat Prod. 2011 Oct 28;74(10):2128-36
diplasterioside B  0   *Saponins Antineoplastic Agents. Bioorg Khim. 2011 Jul-Aug;37(4):559-66
diplasterioside A  0   *Saponins Antineoplastic Agents. Bioorg Khim. 2011 Jul-Aug;37(4):559-66
2alpha,3alpha-dihydroxyurs-12-ene-28-oic acid  0   *Saponins. J Ethnopharmacol. 2011 Jun 1;135(3):626-35
caraganoside D  0   *Saponins *Triterpenes. Arch Pharm Res. 2011 Jun;34(6):869-73
caraganoside C  0   *Saponins *Triterpenes. Arch Pharm Res. 2011 Jun;34(6):869-73
gymnemaside VI  0   *Saponins. Phytochemistry. 2011 Aug;72(11-12):1453-9
apodytine  0   *Saponins Antiprotozoal Agents. Phytochemistry. 2011 Aug;72(11-12):1414-23
dipsacus saponin K  0   *Saponins Oleanolic Acid/*analogs & derivatives. Asian Nat Prod Res. 2011 Sep;13(9):851-60
dipsacus saponin J  0   *Saponins Oleanolic Acid/*analogs & derivatives. Asian Nat Prod Res. 2011 Sep;13(9):851-60
puberoside D  0   *Saponins *Triterpenes. J Asian Nat Prod Res. 2011 Sep;13(9): 838-44
puberoside E  0   *Saponins *Triterpenes. J Asian Nat Prod Res. 2011 Sep;13(9): 838-44
puberoside C  0   *Saponins *Triterpenes. J Asian Nat Prod Res. 2011 Sep;13(9): 838-44
bacosaponin C  0   *Saponins *Triterpenes. Phytomedicine. 2011 Jul 15;18(10):836-42
gymnocladus saponin F2  0   *Saponins. J Asian Nat Prod Res. 2011 Sep;13(9):869-78
gymnocladus saponin E  0   *Saponins. J Asian Nat Prod Res. 2011 Sep;13(9):869-78
3-O-fucopyranosylsaikogenin F  0   *Saponins. Arch Pharm Res 2011 May;34(5):703-7
heloside B  0   *Saponins. J Nat Prod. 2011 Jul 22;74(7):1557-60
heloside A  0   *Saponins. J Nat Prod. 2011 Jul 22;74(7):1557-60
amplexicogenin--3-O-beta-D-cymaropyranosyl-(1-4)-alpha-L-cymaropyranosyl-(1-4)-beta-D-cymaropyranoside  0   *Saponins *Steroids. J Asian Nat Prod Res. 2011 Aug;13(8):756-60
amplexicogenin B-3-O-beta-D-cymaropyranoside  0   *Saponins *Steroids. J Asian Nat Prod Res. 2011 Aug;13(8):756-60
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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