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Retinal Degeneration

More information in Books or onNLM PubMed
Definition: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)     
Examples Macular Degeneration; Retinal Drusen; Retinal Dystrophies; Retinoschisis 		Other names Retinal Degenerations; Degenerations, Retinal; Degeneration, Retinal
 
SubstanceCAS Registry & nameCategoriesSource
MacKay Shek Carr syndrome  0   *Glaucoma *Retinal Degeneration.
Snowflake vitreoretinal degeneration  0   *Retinal Degeneration.
Spastic paraplegia 15, autosomal recessive  0   *Retinal Degeneration *Spastic Paraplegia, Hereditary.
Vitreoretinochoroidopathy dominant  0   *Retinal Degeneration *Eye Diseases, Hereditary *Choroid Diseases.
Joubert syndrome 4  0   *Cerebellar Diseases *Retinal Degeneration *Kidney Diseases, Cystic.
Noble Bass Sherman syndrome  0   *Ectopia Lentis *Myopia *Retinal Degeneration *Choroid Diseases. Doc Ophthalmol. 1993;83(2):97-102
Hyaloideoretinal degeneration of Wagner  0   *Retinal Degeneration.
C1QTNF5 protein, human  0   *Collagen Retinal Degeneration. Hum Mol Genet 2003 Oct 15;12(20):2657-67
BEST1 protein, human  0   *Eye Proteins *Chloride Channels Retinal Degeneration. Hum Mol Genet 1998 Sep;7(9):1517-25; Nat Genet 1998 Jul;19(3):241-7
rdgC protein, Drosophila  EC 3.1.3.16   *Calcium-Binding Proteins *Phosphoprotein Phosphatases *Drosophila Proteins Retinal Degeneration. Cell 1992 May 15;69(4):669-76
peripherin  0   *Intermediate Filament Proteins *Membrane Glycoproteins *Nerve Tissue Proteins Retinal Degeneration Xenopus Proteins. Dev Neurosci 1983-84;6(6):335

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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