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Pyrophosphatases
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Definition
: A group of enzymes within the class EC 3.6.1.- that catalyze the hydrolysis of diphosphate bonds, chiefly in nucleoside di- and triphosphates. They may liberate either a mono- or diphosphate. EC 3.6.1.-.
Examples
Inorganic Pyrophosphatase
;
Thiamine Pyrophosphatase
Substance
CAS Registry & name
Categories
Source
Drugs
*
alpha-
farnesene synthase, E coli
EC 3.6.1.-
*Pyrophosphatases
*Escherichia coli Proteins.
Metab Eng. 2011 Nov;13(6):648-55.
ectonucleoside triphosphate diphosphohydrolase 6, human
EC 3.6.1.-
*Pyrophosphatases.
Oncol Rep 2011 Jul;26(1):161-7
ITPA protein, mouse
EC 3.6.1.19
*Pyrophosphatases.
Mutat Res. 2010 Nov 28;703(1):43-50
MESH1 protein, human
EC 3.6.1.-
*Pyrophosphatases.
Nat Struct Mol Biol 2010 Oct;17(10):1188-94
TPSO3 protein, Arabidopsis
EC 5.5.-
*Multienzyme Complexes
*Pyrophosphatases
*Intramolecular Lyases
*Arabidopsis Proteins.
Plant Physiol 2010 Jul;153(3):1293-310
TPSO2 protein, Arabidopsis
EC 5.5.-
*Multienzyme Complexes
*Pyrophosphatases
*Intramolecular Lyases
*Arabidopsis Proteins.
Plant Physiol 2010 Jul;153(3):1293-310
Aps protein, Drosophila
EC 3.6.1.-
*Pyrophosphatases.
Int J Biochem Cell Biol 2010 Jul;42(7):1174-81
NUDT16 protein, mouse
EC 3.6.1.-
*Pyrophosphatases.
Nucleic Acids Res 2010 May;38(9):2891-903
Orf17 protein, E coli
EC 3.6.1.-
*Pyrophosphatases
*Escherichia coli Proteins.
DNA Repair (Amst) 2005 Jan 2;4(1):33-9
Nudt14 protein, mouse
EC 3.6.1.45
*Pyrophosphatases.
Biochem Biophys Res Commun 2009 Dec 25;390(4):1414-8
NUDX7 protein, Arabidopsis
EC 3.6.1.-
*Pyrophosphatases
*Arabidopsis Proteins.
J Biol Chem 2009 Nov 20;284(47):741-54
MazG protein, E coli
EC 2.6.1.-
*Pyrophosphatases
*Escherichia coli Proteins.
J Mol Biol 2009 Sep 11;392(1):63-74
MTH2 protein, human
EC 2.6.1.-
*Pyrophosphatases.
J Biol Chem 2009 Jul 17;284(29):19310-20
nudix pyrophosphatase 8, Thermus thermophilus
EC 3.6.1.-
*Bacterial Proteins
*Pyrophosphatases.
J Biol Chem 2009 Jun 5;284(23):15549-56
Ysa1 protein, S cerevisiae
EC 3.6.1.13
*Pyrophosphatases
*Saccharomyces cerevisiae Proteins.
J Biol Chem 2009 Apr 24;284(17):11256-66
Enpp3 protein, rat
EC 3.1.4.1
*Phosphoric Diester Hydrolases
*Pyrophosphatases.
J Cell Sci 2007 Mar 15;120(Pt 6):1009-16
Nudt16 protein, human
EC 3.6.1.-
*Pyrophosphatases.
J Biol Chem 2007 Aug 24;282(34):24792-805
RS21-
C6 protein, mouse
EC 3.6.1.23
*Pyrophosphatases.
J Mol Biol. 2007 Apr 13;367(5):1405-12
DPP1 protein, S cerevisiae
EC 3.1.3.-
*Membrane Proteins
*Pyrophosphatases
*Saccharomyces cerevisiae Proteins.
J Biol Chem 1998 Feb 6;273(6):3278-84
YffH protein, E coli
EC 3.6.1.-
*Pyrophosphatases
*Escherichia coli Proteins.
J Biol Chem 2006 Aug 11;281(32):22794-8
YmfB protein, E coli
EC 3.6.1.-
*Pyrophosphatases
*Escherichia coli Proteins.
J Biol Chem 2006 Aug 11;281(32):22794-8
YfaO protein, E coli
EC 3.6.1.-
*Pyrophosphatases
*Escherichia coli Proteins.
J Biol Chem 2006 Aug 11;281(32):22794-8
ITPA protein, human
EC 3.6.1.19
*Pyrophosphatases.
Gut 2006 Jul;55(7):1048; author reply 1048-9
DcpS protein, C elegans
EC 3.6.1.-
*Pyrophosphatases
*Caenorhabditis elegans Proteins.
EMBO J 2002 Sep 2;21(17):4699-708
RP2 protein, mouse
EC 3.6.1.-
*Pyrophosphatases.
Nucleic Acids Res 1986 Jul 11;14(13):5159-70
Npp2 protein, S cerevisiae
EC 3.-
*Hydrolases
*Saccharomyces cerevisiae Proteins
Phosphoric Diester Hydrolases
Pyrophosphatases.
Eukaryot Cell 2005 Nov;4(11):1892-901
Npp1 protein, S cerevisiae
EC 3.-
*Hydrolases
*Saccharomyces cerevisiae Proteins
Phosphoric Diester Hydrolases
Pyrophosphatases.
Eukaryot Cell 2005 Nov;4(11):1892-901
YjjX protein, E coli
EC 3.6.1.-
*Pyrophosphatases.
Structure 2005 Oct;13(10):1511-20
undecaprenyl pyrophosphate phosphatase
EC 3.6.1.-
*Pyrophosphatases.
J Biol Chem 2005 Aug 12;280(32):28852-7
X29 protein, Xenopus
EC 3.6.1.-
*Pyrophosphatases
*Xenopus Proteins
RNA-Binding Proteins.
Mol Cell 2004 Mar 26;13(6):817-28
ENTPD4 protein, human
EC 3.6.1.6
*Pyrophosphatases.
BMC Biochem 2004 Jun 16;5(1);8
Lysal2 protein, mouse
EC 3.6.1.5
*Pyrophosphatases.
VSP1 protein, Trypanosoma brucei
EC 3.6.1.-
*Pyrophosphatases
*Protozoan Proteins.
J Biol Chem 2004 Jan 30;279(5):3420-5
NUDT12 protein, human
EC 3.6.1.-
*Pyrophosphatases.
Biochem J 2003 Sep 1;374(Pt 2);329-35
RdgB protein, E coli
EC 3.6.1.-
*Pyrophosphatases
*Escherichia coli Proteins
DNA Repair.
J Bacteriol 2003 May;185(10):3101-10
NUDT1 protein, Arabidopsis
EC 3.6.1.-
*Pyrophosphatases
*Arabidopsis Proteins.
J Biol Chem 2002 Dec 27;277(52):50482-6
Dolpp1 protein, mouse
EC 3.6.1.43
*Pyrophosphatases.
J Biol Chem 2002 Nov 22;277(47):45226-34
NUDT10 protein, human
EC 3.6.1.-
*Pyrophosphatases.
BMC Biochem 2002 Jul 16;3(1):20
NUDT11 protein, human
EC 3.6.1.-
*Pyrophosphatases.
BMC Biochem 2002 Jul 16;3(1):20
UDP-
2,3-
diacylglucosamine pyrophosphatase
EC 3.6.1.-
*Pyrophosphatases
Escherichia coli Proteins.
J Biol Chem 2002 Jul 19;277(29):25937-46
diphosphonucleotide phosphatase-
phosphodiesterase 2
EC 3.6.1.-
*Phosphoric Diester Hydrolases
*Pyrophosphatases.
FEBS Lett 2002 May 22;519(1-3):159-63
diphosphonucleotide phosphatase-
phosphodiesterase 1
EC 3.6.1.-
*Phosphoric Diester Hydrolases
*Pyrophosphatases.
FEBS Lett 2002 May 22;519(1-3):159-63
pyrophosphatase, Aquifex aeolicus
EC 3.6.1.-
*Bacterial Proteins
*Pyrophosphatases.
Protein Expr Purif 2001 Nov;23(2):242-8
nucleoside-
triphosphate diphosphohydrolase 3
EC 3.6.1.-
*Pyrophosphatases.
Arch Biochem Biophys 2001 Nov 1;395(1):94-102
NadN protein, Haemophilus influenzae
EC 3.6.1.-
*Bacterial Proteins
*Nucleotidases
*Pyrophosphatases.
J Bacteriol 2001 Jul;183(13):3974-81
NUDT9
EC 3.6.1.-
*Pyrophosphatases.
Nature 2001 May 31;411(6837):595-9
ENPP3 protein, human
0
*Phosphoric Diester Hydrolases
*Pyrophosphatases.
Blood 2001 May 15;97(10):3303-5
NPY1 protein, S cerevisiae
EC 3.6.1.-
*Pyrophosphatases
*Saccharomyces cerevisiae Proteins.
Arch Biochem Biophys 2001 Apr 1;388(1):18-24
TVP protein, Thermotoga maritima
EC 3.6.1.-
*Bacterial Proteins
*Pyrophosphatases.
FEBS Lett 2001 May 4;496(1):6-11
nudix hydrolase Orf135
EC 3.6.1.-
*Pyrophosphatases.
J Biol Chem 2001 Feb 23;276(8):5421-6
nucleoside triphosphate diphosphohydrolase 6
EC 3.6.1.-
*Pyrophosphatases.
Biochem J 2000 Nov 1;351 Pt 3:639-47
triphenyltin salicylate
0
*Organotin Compounds
*Salicylates
Pyrophosphatases.
J Enzyme Inhib 2000 Jun;15(4):411-20
nucleotide pyrophosphatase -
phosphodiesterase I
EC 3.6.1.-
*Phosphoric Diester Hydrolases
*Pyrophosphatases.
Biochem J 2000 Feb 15;346( Pt 1):25-31
NUDT5 protein, human
EC 3.6.1.-
*Pyrophosphatases.
Biochem J 1999 Dec 1;344( Pt 2):331-7
aps1 protein, S pombe
EC 3.6.1.-
*Pyrophosphatases
*Schizosaccharomyces pombe Proteins.
Biochemistry 1999 mar 23;38(12):3649-55
SLR0787 protein, Synechocystis
EC 2.7.7.1
*Bacterial Proteins
*Nicotinamide-Nucleotide Adenylyltransferase
*Pyrophosphatases.
FEBS Lett 1999 Feb 12;444(2-3):222-6
CAX4 protein, S cerevisiae
0
*Pyrophosphatases
*Saccharomyces cerevisiae Proteins.
Glycobiology 1999 Mar;9(3):243-53
ENTPD5 protein, human
EC 3.6.1.-
*Pyrophosphatases
*Oncogene Proteins.
Oncogene 1999 Jan 21;18(3):689-701
Nurf-
38 protein, Drosophila
EC 3.6.1.1
*Pyrophosphatases
*Drosophila Proteins.
Genes Dev 1998 Oct 15;12(20):3206-16
CILP protein, human
EC 3.6.1.-
*Pyrophosphatases
*Extracellular Matrix Proteins
Glycoproteins.
J Biol Chem 1998 Sep 4;273(36):23463-8
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