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Poly I

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Definition: A group of inosine ribonucleotides in which the phosphate residues of each inosine ribonucleotide act as bridges in forming diester linkages between the ribose moieties.  do not confuse with POLY I-C   
Examples Poly I-C
Other names Polyinosinic Acids; Inosine Polynucleotides; Polynucleotides, Inosine; Acids, Polyinosinic
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
poly(2-methylthio-7-deazainosinic acid)  88357-67-9 4H-Pyrrolo(2,3-d)pyrimidin-4-one, 1,7-dihydro-2-(methylthio)-7-(5-O-phosphono-beta-D-ribofuranosyl)-, homopolymer  *Poly I. Nucleic Acids Res 1983;11(17):6107
poly-8-oxyinosinic acid  83614-18-0 5'-Inosinic acid, 7,8-dihydro-8-oxo-, homopolymer  *Poly I. J Biochem (Tokyo) 1982;92(3):961
poly(1-methyl-6-thioinosinic acid)  59911-56-7   *Poly I *Thionucleotides. J Gen Virol 1981;52(2):291
poly(thioinosinic acid)  59126-38-4   *Poly I *Thionucleotides. J Gen Virol 1981;52(2):291
poly(2'-chloro-2'-deoxyinosinic acid)  70368-43-3 5'-Inosinic acid, 2'-chloro-2'-deoxy-, homopolymer  *Poly I *Polydeoxyribonucleotides. Nucleic Acids Res 6(7):2627;1979
poly(1-methylinosinic acid)  29855-89-8 5'-Inosinic acid, 1-methyl-, homopolymer  *Poly I. Nucleic Acids Res 6(3):1049;1979
poly(2-azainosinic acid)  65170-09-4 4H-Imidazo(4,5-d)-1,2,3-triazin-4-one, 1,7-dihydro-7-(5-O-phosphono-beta-D-ribofuranosyl)-, homopolymer  *Poly I. Biochim Biophys Acta 520(2):441;1978
poly If  68777-95-7 5'-Inosinic acid, 2'-deoxy-2'-fluoro-, homopolymer  *Poly I. Nucleic Acids Res 5(9):3347;1978
poly(2-methylthioinosinic acid)  37100-40-6   *Poly I. Nucleic Acids Res 2(12):2305;1975
poly(7-deazainosinic acid)  53794-83-5   *Poly I. Biochemistry 13(21):4400;1974; Mol Pharmacol 12:1045;1976; Nucleic Acid Res 3(6):1591;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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