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Placental Lactogen

More information in Books or onNLM PubMed
Definition: A polypeptide hormone of approximately 25 kDa that is produced by the SYNCYTIOTROPHOBLASTS of the PLACENTA, also known as chorionic somatomammotropin. It has both GROWTH HORMONE and PROLACTIN activities on growth, lactation, and luteal steroid production. In women, placental lactogen secretion begins soon after implantation and increases to 1 g or more a day in late pregnancy. Placental lactogen is also an insulin antagonist.     
See Also Receptors, Somatotropin 		Other names Somatomammotropin, Chorionic; Mammotropic Hormone, Placental; Lactogen Hormone, Placental; Human Placental Lactogen; Chorionic Somatomammotropin, Human; Choriomammotropin; Pregnancy Associated Plasma Protein D; Placental Mammotropic Hormone; Placental Lactogen, Human; Luteotropin, Placental; Lactogen, Placental; Human Chorionic Somatomammotropin; Chorionic Somatomammotropin; Pregnancy-Associated Plasma Protein D; Placental Luteotropin; PAPP-D; HPL (Human Placental Lactogen); HCS (Human Chorionic Somatomammotropin); Choriomammotrophin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
placental lactogen-3, human  0   *Placental Lactogen. Placenta 2006 Apr-May;27(4-5):357-66
placental lactogen A-2  0   *Placental Lactogen *Human Growth Hormone. Mol Cell Endocrinol. 2000 Sep 25;167(1-2):117-25
placental lactogen I, rat  149146-52-1 Lactogen I, placental  *Placental Lactogen. J Endocrinol 1993 Nov;139(2):235-42
placental lactogen I-variant  0   *Placental Lactogen. J Biol Chem 1991;266(3):1605
placental lactogen II  0   *Placental Lactogen. Mol Endocrinol 1989;3(11):1710

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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