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Phosphopyruvate Hydratase

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Definition: A hydro-lyase that catalyzes the dehydration of 2-phosphoglycerate to form PHOSPHOENOLPYRUVATE. Several different isoforms of this enzyme exist, each with its own tissue specificity.     
Examples tau-Crystallins 		Other names Neuron-Specific Enolase; Enolase; gamma Enolase; beta Enolase; alpha Enolase; System-Specific Enolase, Nervous; Non Neuronal Enolase; Neuron Specific Enolase; Nervous System Specific Enolase; Muscle Specific Enolase; Hydro-Lyase, 2-Phospho-D-Glycerate; Hydratase, Phosphopyruvate; Enolase, Non-Neuronal; Enolase, Neuron-Specific; Enolase, Nervous System-Specific; Enolase, Muscle-Specific; Dehydratase, 2-Phosphoglycerate; 2 Phosphoglycerate Dehydratase; 2 Phospho D Glycerate Hydrolase; 2 Phospho D Glycerate Hydro Lyase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
enolase 2, zebrafish  EC 4.2.1.11   *Phosphopyruvate Hydratase *Zebrafish Proteins. Nucleic Acids Res 2007;35(19):6501-16
ENO1 protein, S cerevisiae  EC 4.2.1.11   *Phosphopyruvate Hydratase *Saccharomyces cerevisiae Proteins. Eukaryot Cell 2007 May;6(5):786-96
enolase 2, S cerevisiae  EC 4.2.1.11   *Phosphopyruvate Hydratase *Saccharomyces cerevisiae Proteins. FEBS J 2006 Dec;273(23):5273-87
alpha-enolase P46, Bacteroides fragilis  EC 4.2.1.11   *Phosphopyruvate Hydratase. Microbes Infect 2005 Jan;7(1):9-18
alpha-enolase, Onchocerca volvulus  EC 4.2.1.11   *Phosphopyruvate Hydratase. Biochim Biophys Acta 2003 Jun 19;1627(2-3):111-20
Eno1 protein, mouse  EC 4.2.1.11   *Phosphopyruvate Hydratase. Infect Immun 2002 Jun;70(6):3281-3
Hev b 9 allergen  EC 4.2.1.-   *Allergens *Phosphopyruvate Hydratase *Plant Proteins Latex Hevea. Eur J Biochem 2000 Dec;267(24):7006-14
streptococcal surface enolase  EC 4.2.1.-   *Bacterial Proteins *Phosphopyruvate Hydratase. J Biol Chem 1998 Jun 5;273(23):14503-15
ENO1 protein, human  EC 4.2.1.11   *DNA-Binding Proteins *Phosphopyruvate Hydratase *Tumor Markers, Biological *Tumor Suppressor Proteins tau-Crystallins. Cancer Res 1995 Sep 1;55(17):3747-51
carboxyphosphonoenolpyruvate synthase  EC 4.2.1.-   *Phosphopyruvate Hydratase. Gene 1995 Feb 3;153(1):143-4

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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