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Penicillin Amidase

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Definition: An enzyme catalyzing the hydrolysis of penicillin to penicin and a carboxylic acid anion. EC 3.5.1.11.      Other names Penicillin Amidohydrolase; Penicillin Acylase; Amidohydrolase, Penicillin; Amidase, Penicillin; Acylase, Penicillin V; Acylase, Penicillin G; Acylase, Penicillin; Acylase, Cephalosporin; Acylase, Benzylpenicillin; Penicillin V Acylase; Penicillin G Acylase; Cephalosporin Acylase; Benzylpenicillin Acylase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
7-bromoacetyl aminocephalosporanic acid  0   *Cephalosporins Penicillin Amidase/antagonists & inhibitors. J Biol Chem 2002 Mar 22;277(12):10256-64
phenoxymethylpenicillin amidohydrolase  EC 3.5.1.-   *Penicillin Amidase. FEBS Lett 1996 Sep 23;394(1):31-3
ampicillin acylase  EC 3.5.1.-   *Penicillin Amidase. Wei Sheng Wu Hsueh Pao 1986;26(2):154
glutarylamidocephalosporanic acid acylase  EC 3.5.1.11   *Penicillin Amidase. J Bacteriol 1985;163(3):1222

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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