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Nordihydroguaiaretic Acid

More information in Books or onNLM PubMed
Definition: A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.  DF: NDGA   
Pharmacological Action Antioxidants; Cyclooxygenase Inhibitors; Lipoxygenase Inhibitors 		Other names meso-Nordihydroguaiaretic Acid; Nordihydroguaiaretic Acid, (R*,S*)-Isomer; Masoprocol; Dihydronorguaiaretic Acid; Actinex; 4,4'-(2,3 Dimethyl-1,4-butanediyl)bis(1,2-benzenedDrugs* : ACTINEX
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
maltose-tri-O-methyl nordihydroguaiaretic acid  0   *Monosaccharides Nordihydroguaiaretic Acid/*analogs & derivatives. Cancer Chemother Pharmacol. 2006 Nov;58(5):640-53
nordy  0   Nordihydroguaiaretic Acid/*analogs & derivatives. Int Immunopharmacol 2006 Jan;6(1):90-9
terameprocol  5701-82-6   Nordihydroguaiaretic Acid/*analogs & derivatives. Biosci Biotechnol Biochem 1992 Jul;56(7):1162-3
heminordihydroguaiaretic acid  54473-24-4   Nordihydroguaiaretic Acid/*analogs & derivatives. Biochim Biophys Acta 1984;788(2):167

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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