encyclopedia of medical concepts
ψ 

Netropsin

More information in Books or onNLM PubMed
Definition: A basic polypeptide isolated from Streptomyces netropsis. It is cytotoxic and its strong, specific binding to A-T areas of DNA is useful to genetics research.     
Pharmacological Action Anti-Bacterial Agents; Antiviral Agents 		Other names Sinanomycin; Hydrochloride, Netropsin; Netropsin Hydrochloride; Congocidine; IA-887; T-1384
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
proximicin C  0   Netropsin/*analogs & derivatives. Angew Chem Int Ed Engl 2008;47(17):3258-61
proximicin B  0   Netropsin/*analogs & derivatives. Angew Chem Int Ed Engl 2008;47(17):3258-61
proximicin A  0   Netropsin/*analogs & derivatives. Angew Chem Int Ed Engl 2008;47(17):3258-61
acridine-netropsin hybrid molecule  0   *Acridines Netropsin/*analogs & derivatives. Nucleic Acids Symp Ser 1999 ;(42):247-8
5-(2-(2-(2-(2--(dimethylaminoethylaminocarbonyl)-1-methylpyrrol-4-yl)aminocarbonyl-1-methylpyrrol-4-yl)aminocarbonylpropylaminocarbonyl-1-methylpyrrol-4-yl)aminocarbonyl-1-methylpyrrol-4-yl)aminocarbonylpentahydroxamic acid  0   *Hydroxamic Acids Netropsin/*analogs & derivatives. Nucleic Acids Symp Ser 1997;(37):7-8
5-(2-(2-(2-(2-(dimethylaminoethylaminocarbonyl)-1-methylpyrrol-4-yl)aminocarbonyl-1-methylpyrrol-4-yl)aminocarbonylethylaminocarbonyl-1-methylpyrrol-4-yl)aminocarbonyl-1-methylpyrrol-4-yl)aminocarbonylpentahydroxamic acid  0   *Hydroxamic Acids Netropsin/*analogs & derivatives. Nucleic Acids Symp Ser 1997;(37):7-8
methyl lexitropsin  0   Netropsin/*analogs & derivatives. J Biol Chem 1998 Feb 27;273(9):5412-8
di-imidazole lexitropsin  0   Netropsin/*analogs & derivatives. Structure 1997 Aug 15;5(8):1033-46
bis(netropsin)-anthracenedione conjugate  0   *Anthraquinones Netropsin/*analogs & derivatives. Anticancer Drug Des 1997 Sep;12(6):481-501
1-methyl-4-(((1-methyl-4-((3-((methylsulfonyl)oxy)-1-oxopropyl)amino)-1H-pyrrol-2-yl)carbonyl)amino)-N-propyl-1H-pyrrole-2-carboxamide  148965-72-4   Netropsin/*analogs & derivatives. Biochem 1993 Aug 10;32(31):7954-65
ThiaNetGA  0   Netropsin/*analogs & derivatives. Bioconjug Chem 1994 Sep-Oct;5(5):475-81
pyridine-2-carboxamidonetropsin  0   Netropsin/*analogs & derivatives. Biochemistry 1993 Oct 26;32(42):11385-9
1-methylimidazole-2-carboxamide netropsin  129601-50-9   Netropsin/*analogs & derivatives. Proc Natl Acad Sci U S A 1992 Aug 15;89(16):7586-90
lexitropsin 1  123725-00-8 5-Thiazolecarboxamide, N-(3-amino-3-iminopropyl)-2-(((4-(formylamino)-1-methyl-1H-pyrrol-2-yl)carbonyl)amino)-4-methyl  *Thiazoles Netropsin/*analogs & derivatives. J Biomol Struct Dyn 1991 Aug;9(1):001-021
Pt-bis-netropsin  132642-25-2   *Organoplatinum Compounds Netropsin/*analogs & derivatives. Nucleic Acids Res 1991;19(2):257
netropsin-oxazolopyridocarbazole  130861-48-2   *Carbazoles Netropsin/*analogs & derivatives. Biochemistry 1991;30(6):1642
bis(furan)lexitropsin  125746-78-3   Netropsin/*analogs & derivatives. J Mol Recognit 1989;2(2):84
bis-N-methylimidazolelexitropsin  0   Netropsin/*analogs & derivatives. Electrophoresis 1989;10(5-6):404
lexitropsin  110124-49-7   Netropsin/*analogs & derivatives.
Pharma Action Antineoplastic Agents ; Antiviral Agents 		Dokl Akad Nauk SSSR 1987;294(5):1243
bis-netropsin  75472-88-7 Dodecanediamide, N,N'-bis(2-((5-(((5-(((3-amino-3-iminopropyl)amino)carbonyl)-1-propyl-1H-pyrrol-3-yl)amino)carbonyl)-1-propyl-1H-pyrrol-3-yl)amino)-2-oxoethyl)-, dihydrochloride  Netropsin/*analogs & derivatives. Biokhimiia 1981;25991):244

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy