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Monensin

More information in Books or onNLM PubMed
Definition: An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts' development of acquired immunity to the majority of coccidial species. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies.     
Pharmacological Action Antifungal Agents; Antiprotozoal Agents; Coccidiostats; Proton Ionophores; Sodium Ionophores 		Other names Monensin A Sodium Complex; Rumensin; Monensin-A-Sodium Complex; Monensin Sodium; Monensin Monosodium Salt; Coban
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
7-oxomonensin  0   Monensin/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1997 Jun;45(6):966-70
2-demethylmonensin B  0   Monensin/*analogs & derivatives. J Antibiot (Tokyo) 1996 Sep;49(9):935-7
2-demethylmonensin A  0   Monensin/*analogs & derivatives. J Antibiot (Tokyo) 1996 Sep;49(9):935-7
26-deoxymonensin B  155539-11-0   Monensin/analogs & derivatives. Appl Environ Microbiol 1994 May;60(5):1561-4
CP 82996  127288-12-4   Monensin/analogs & derivatives. J Ind Microbiol 1990;6(2):135
26-deoxylaidlomycin  102674-88-4 Monensin, 16-deethyl-3-O-demethyl-26-deoxy-16-methyl-3-O-(1-oxopropyl)  Monensin/*analogs & derivatives. J Basic Microbiol 1989;29(6):391
26-deoxymonensin A  122576-59-4 Monensin, 26-deoxy  Monensin/analogs & derivatives. J Antibiot (Tokyo) 1989;42(7):1088
3-O-demethylmonensin B  109345-56-4   Monensin/analogs & derivatives. J Antibiot (Tokyo) 1987;40(4):555
3-O-demethylmonensin A  92096-16-7   Monensin/analogs & derivatives. J Antibiot (Tokyo) 1987;40(4):555
monensin methyl ester  28636-21-7 Monensin, methyl ester  Monensin/*analogs & derivatives. Biomed Tech (Berlin) 1987;32(1-2):22
laidlomycin phenylcarbamate  101191-83-7   *Phenylcarbamates Monensin/analogs & derivatives. J Antibiot (Tokyo) 1986;39(12):1765
monensin B  30485-16-6   Monensin/*analogs & derivatives. Biochem Soc Trans 1984;12(4):587
laidlomycin butyrate  78734-45-9   Monensin/*analogs & derivatives Ionophores. J Anim Sci 1983;57(6):1553
X 14667B  75761-61-4 Monensin, 26-((2-phenylethyl)carbamate)  Monensin/*analogs & derivatives Ionophores. J Antibiot (Tokyo) 1981;34(10):1241
X 14667A  75761-62-5 Monensin, 16-deethyl-16-methyl-, 26-((2-phenylethyl)carbamate)  Monensin/*analogs & derivatives Ionophores. J Antibiot (Tokyo) 1981;34(10):1241
laidlomycin  56283-74-0 Monensin, 16-deethyl-3-O-demethyl-16-methyl-3-O-(1-oxopropyl)  Monensin/*analogs & derivatives. J Antibiot 27:884;1974; J Antibiot 29(7):761;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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