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Mineralocorticoids

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Definition: A group of CORTICOSTEROIDS primarily associated with the water and electrolyte balance. This is accomplished through the effect on ION TRANSPORT in renal tubules, resulting in retention of sodium and loss of potassium. Mineralocorticoid secretion is itself regulated by PLASMA VOLUME, serum potassium, and ANGIOTENSIN II.  note entry term MINERALOCORTICOID EFFECT: use only for the mineralocorticoid effect of a chemical substance    Other names Effects, Mineralocorticoid; Effect, Mineralocorticoid; Mineralocorticoid Effects; Mineralocorticoid Effect
Substances having this pharmacologic action: Desoxycorticosterone
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-hydroxyaldosterone  147199-27-7   Aldosterone/*analogs & derivatives Mineralocorticoids. Steroids 1993 Feb;58(2):59-63
ZK 91587  84542-26-7 3'H-Cyclopropa(15,16)pregna-4,15-diene-7,21-dicarboxylic acid, 15,16-dihydro-17-hydroxy-3-oxo-, gamma-lactone, methyl ester, (7alpha,15alpha,16alpha,17alpha)  Spironolactone/*analogs & derivatives Mineralocorticoids/antagonists & inhibitors. Biochim Biophys Acta 1988;964(1):105

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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