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Methoxsalen

More information in Books or onNLM PubMed
Definition: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.  do not index here for use in PUVA THERAPY unless particularly discussed   
Pharmacological Action Cross-Linking Reagents; Photosensitizing Agents 		Other names Xanthotoxin; Ammoidin; 8-Methoxypsoralen; 8MOP; Sanofi Synthelabo Brand of Methoxsalen; Oxsoralen Ultra; Mex America Brand of Methoxsalen; Methoxsalen Sanofi-Synthelabo Brand; Methoxsalen Mex-America Brand; Methoxsalen Dermatech Brand; Methoxsalen Delta Brand; Methoxsalen Chinoin Brand; Methoxsalen Canderm Brand; Methoxa Dome; 8 Methoxypsoralen; 8 MOP; Ultramop; Sanofi-Synthelabo Brand of Methoxsalen; Puvalen; Oxsoralen-UltraDrugs* : UVADEX; METHOXSALEN; OXSORALEN; 8-MOP; OXSORALEN-ULTRA
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-hydroxy-8-methoxypsoralen  0   Methoxsalen/*analogs & derivatives. Yao Xue Xue Bao 2007 May;42(5):505-10
4-bromo-8-methoxypsoralen  0   Methoxsalen/*analogs & derivatives. J Photochem Photobiol B 2008 Sep 18;92(3):185-9
graveoline  0   Methoxsalen/*analogs & derivatives. J Agric Food Chem. 2004 Jun 2;52(11):3345-9
4-tert-butylperoxymethyl-9-methoxypsoralen  0   Methoxsalen/*analogs & derivatives. Photochem Photobiol 1998 Oct;68(4):511-8
5-methoxypsoralen-thymidine adduct  0   Methoxsalen/*analogs & derivatives Thymidine/*analogs & derivatives. J Photochem Photobiol B 1995 Feb;27(2):167-75
1-thiomethoxsalen  0   Methoxsalen/*analogs & derivatives. J Med Chem 1995 Mar 17;38(6):869-74
8-methoxythionepsoralen  72142-97-3   *Thiones Methoxsalen/*analogs & derivatives. Photochem Photobiol 1992 Sep;56(3):341-52
3,4'-dimethyl-8-methoxypsoralen  85985-46-2   Methoxsalen/*analogs & derivatives. Photochem Photobiol 1990;52(3):533
8-methoxypsoralen-DNA  0   *Methoxsalen *DNA Adducts. Cancer Res 1988;48(24 Pt 1):7013
thymidine-8-methoxypsoralen tetramethylethylene diadduct  94591-68-1 2H-Cyclobuta(4'',5'')pyrano(3'',2'':5',6')benzofuro(3',2':3,4)cyclobuta(1,2-d)pyrimidine-3,8,10(1H,6aH,9H)-trione, 7-(2-deoxy-beta-D-erythro-pentofuranosyl)-2a,6b,7,10a,10b,11b-hexahydro-5-methoxy-1,1,2,2,10a-pentamethyl-, (2S-(2alpha,5alpha,6beta(S*)))  Methoxsalen/*analogs & derivatives Thymidine/*analogs & derivatives. Photochem Photobiol 1984;40(2):171
sphondin  483-66-9   Methoxsalen/*analogs & derivatives. Contact Dermatitis 1983;9(5):364
pimpinellin  131-12-4   Methoxsalen/*analogs & derivatives. Contact Dermatitis 1983;9(5):364
beroxan  8015-45-0 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-methoxy-, mixt. with 9-methoxy-7H-furo(3,2-g)(1)benzopyran-7-one  *Methoxsalen Drug Combinations. Radiobiologiia 19(6):833;1979
5-methoxypsoralen  484-20-8 4-methoxy-7H-furo(3,2-g)(1)benzopyran-7-one  Methoxsalen/*analogs & derivatives Dermotoxins Dermatitis, Phototoxic.
Pharma Action Photosensitizing Agents 		Radiolbiologiia 19(6):833;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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