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Melanins

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Definition: Insoluble polymers of TYROSINE derivatives found in and causing darkness in skin (SKIN PIGMENTATION), hair, and feathers providing protection against SUNBURN induced by SUNLIGHT. CAROTENES contribute yellow and red coloration.      Other names Phaeomelanins; Melanin; Allomelanins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(2Z,8Z)-matricaria acid methyl ester  0   *Polyacetylenes Melanins/antagonists & inhibitors. Biol Pharm Bull. 2009 Jun;32(6):1091-4
cysteinyldopa-melanin  0   *Melanins Cysteinyldopa/*analogs & derivatives. J Phys Chem B 2006 Jul 20;110(28):13985-90
hexahydroxyperylenequinone melanin  0   *Melanins Perylene/*analogs & derivatives. J Bacteriol. 2005 Dec;187(23):8149-55
1,8-dihydroxynaphthalene monoglucoside  0   *Glucosides *Naphthols Melanins. Can J Microbiol 2002 Apr;48(4):320-5
dihydroxyindole-melanin  0   *Indoles *Melanins. J Inorg Biochem 2002 Apr 10;89(1-2):54-60
1,8-dihydroxynaphthalene melanin  0   *Melanins *Naphthols. Infect Immun 2001 Mar;69(3):1781-94
melanin-concentrating hormone, Phe(13),Tyr(19)  0   *Hypothalamic Hormones *Melanins *Pituitary Hormones. J Neurochem 2000 Jan;74(1):385-91
(4-benzoylphenylalanyl(13),tyrosyl(19))-melanin  0   *Melanins. J Pept Sci 1999 May;5(5):234-42
MR 566B  0   *Cyclopentanes *Nitriles Melanins/antagonists & inhibitors. J Antibiot (Tokyo) 1997 Jun;50(6):469-73
MR 566A  0   *Cyclopentanes *Nitriles Melanins/antagonists & inhibitors. J Antibiot (Tokyo) 1997 Jun;50(6):469-73
melanin-concentrating hormone (2-17)  0   *Peptide Fragments *Pituitary Hormones Hypothalamic Hormones Melanins. Peptides 1995;16(5):945-9
3,4',5-trihydroxystilbene-4'-O-(6''-O-galloyl)glucopyranoside  80446-63-5   *Glucosides *Stilbenes Melanins/antagonists & inhibitors Monophenol Monooxygenase/antagonists & inhibitors. Planta Med 1995 Oct;61(5):425-8
3,4',5-trihydroxystilbene-4'-O-(2''-O-galloyl)glucopyranoside  105304-51-6   *Glucosides *Stilbenes Melanins/antagonists & inhibitors Monophenol Monooxygenase/antagonists & inhibitors. Planta Med 1995 Oct;61(5):425-8
opiomelanin  0   *Melanins *Opioid Peptides. Biochim Biophys Acta 1995 Jan 18;1243(1):71-7
dopamine melanin  0   *Melanins. J Neurochem 1993 Jul;61(1):68-79
BU 3619E  132702-35-3 BU 3619E  Melanins/*antagonists & inhibitors. J Antibiot (Tokyo) 1990;43(12):1601
diazoluminolmelanin  126815-81-4   *Melanins Luminol/*analogs & derivatives Biopolymers. Free Radic Res Commun 8(2):115
lipopigments  0   *Lipids Melanins Skin Pigmentation. Mech Ageing Dev 1986;37(1):79
enomelanin  101802-09-9   *Melanins. Farmakol Toksikol 1986;49(4):89
SM II  0   *Melanins Invertebrate Hormones Decapodiformes. Chem Pharm Bull (Tokyo) 1985;33(5):2052
eumelanin  12627-86-0   *Melanins. J Invest Dermatol 1984;83(1):12
5,6-dihydroxytryptamine-melanin  0   *Melanins. Prog Clin Biol Res 1981;59(A):187
fluorescent age pigment  0   *Melanins Aging Fluorescent Dyes Lipid Peroxidation. Mech Ageing Dev 1981;15(3):243
methoxymelanin  69845-43-8 acetamide, N-(2-(5,6-dimethoxy-1H-indol-3-yl)ethyl)  *Melanins. FEBS Lett 1980;122(2):237
melanin precursors  0   *Melanins. J Protozool 1980;27(3):339
Thormaehlen positive melanogens  0   *Melanins. Eur J Cancer 1980;16(3):383
pyomelanin  0   *Melanins. Microbiol Immunol 1980;24(1):1
melanoproteins  0   *Melanins *Proteins Eye Proteins. Biochim Biophys Acta 583(3):378;1979
melanin-concentrating hormone  67382-96-1   *Hypothalamic Hormones *Melanins *Pituitary Hormones Melanophores. Gen Comp Endocrinol 37(1):64;1979
pheomelanin  0   *Melanins. Proc Natl Acad Sci USA 75(11):5395;1978
phaeomelanin  12627-61-1 Phaeomelanin  *Melanins. Acta Derm Venereol (Stockh) 1979;59(5):453; Photochem Photobiol 26(6):651;1977
neuromelanin  0   *Melanins. J Neuropathol Exp Neurol 36(2):379;1977
melanogen  0   *Indoles Melanins. Acta Univ Carol (Med Monogr) (Praha) 78(pt.2):139;1977; Eur J Cancer 14:377;1978; J Chromatogr 154(1):117-22;1978; Lab Anim 9(1):21;1975; Neoplasma 1979;26(5):597

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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