Definition: Pore forming proteins originally discovered for toxic activity to LEUKOCYTES. They are EXOTOXINS produced by some pathogenic STAPHYLOCOCCUS and STREPTOCOCCUS that destroy leukocytes by lysis of the cytoplasmic granules and are partially responsible for the pathogenicity of the organisms.
/antag permitted but consider also ANTITOXINS
Pharmacological ActionCytotoxins
Other names Proteins, Leukocidin; Leukocidin Proteins; Leukocidin; Leucocidin