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Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)

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Definition: An enzyme that catalyzes the synthesis of fructose-6-phosphate plus GLUTAMINE from GLUTAMATE plus glucosamine-6-phosphate.      Other names Hexosephosphate Aminotransferase; Glucosaminephosphate Isomerase (Glutamine-Forming); Glucosamine Synthetase; Ketol-Isomerase, 2-Amino-2-Deoxy-D-Glucose-6-Phosp; Glutamine:Fructose 6 Phosphate Amidotransferase; Glutamine Fructose 6 Phosphate Aminotransferase; Glutamine Fructose 6 P Aminotransferase; Glucosamine 6 Phosphate Synthetase; Glucosamine 6 Phosphate Synthase; Aminotransferase, Glutamine-Fructose-6-Phosphate; Aminotransferase, Hexosephosphate; Aminotransferase, Glutamine-Fructose-6-P; 6-Phosphate Synthetase, Glucosamine; 2 Amino 2 Deoxy D Glucose 6 Phosphate Ketol Isomer; Glutamine:Fructose-6-Phosphate-Amidotransferase; Glutamine-Fructose-6-Phosphate Aminotransferase; Glutamine-Fructose-6-P Aminotransferase; Glucosaminephosphate Isomerase (Glutamine Forming); Glucosamine-6-Phosphate Synthase; Glucosamine 6-Phosphate Synthetase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
GFPT1 protein, human  EC 2.6.1.16   *Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing). J Biol Chem 1992 Dec 15;267(35):25208-12
GFPT2 protein, human  EC 2.6.1.16   *Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing). J Clin Endocrinol Metab 2004 Feb;89(2):748-55
arabinose oxime 5-phosphate  0   *Oximes *Sugar Phosphates Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)/antagonists & inhibitors. J Biol Chem 2000 Jan 7;275(1):135-40
2-deoxyglucitol 6-phosphate  0   *Sugar Phosphates Sorbitol/*analogs & derivatives Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)/antagonists & inhibitors. J Biol Chem 2000 Jan 7;275(1):135-40
GFA1 protein, S cerevisiae  EC 2.6.1.16   *Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing) *Saccharomyces cerevisiae Proteins. J Bacteriol 1996 Apr;178(8):2320-7
N(3)-(chloroacetyl)-2,3-diaminopropanoic acid  135630-95-4   beta-Alanine/*analogs & derivatives Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)/antagonists & inhibitors. Biochim Biophys Acta 1992 Jan 23;1115(3):225-9
N(3)-(bromoacetyl)-2,3-diaminopropanoic acid  77215-58-8   beta-Alanine/*analogs & derivatives Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)/antagonists & inhibitors. Biochim Biophys Acta 1992 Jan 23;1115(3):225-9
nodM protein, Rhizobium  EC 2.6.1.16   *Bacterial Proteins *Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing). J Bacteriol 1991;173(9):2791
norvalyl-N(3)-(4-methoxyfumaroyl)-2,3-diaminopropionic acid  108340-69-8   *Dipeptides Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)/antagonists & inhibitors. Antimicrob Agents Chemother 1991;35(1):36
N(3)-(4-methoxyfumaroyl)-2,3-diaminopropionic acid  96920-07-9   *Fumarates beta-Alanine/*analogs & derivatives Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)/antagonists & inhibitors. Biochemistry 1988;27(7):2282
2-amino-2-deoxyglucitol  14307-03-0 D-Glucitol, 2-amino-2-deoxy  Glucosamine/*analogs & derivatives Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)/antagonists & inhibitors. Biochem Biophys Res Commun 89(2):410;1979; J Biochem (Tokyo) 71(5):909;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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