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Gliotoxin

More information in Books or onNLM PubMed
Definition: A fungal toxin produced by various species of Trichoderma, Gladiocladium fimbriatum, Aspergillus fumigatus, and Penicillium. It is used as an immunosuppressive agent.  /antag permitted but consider also ANTITOXINS;/biosyn permitted if by fungus   
Pharmacological Action Immunosuppressive Agents
Other names Gliotoxins; Aspergillin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
dehydroxybisdethiobis(methylthio)gliotoxin  0   *Gliotoxin. J Antibiot (Tokyo) 2006 Apr;59(4):248-50
methylthiogliotoxin  0   Gliotoxin/*analogs & derivatives. Arch Pharm Res 2001 Oct;24(5):397-401
gliotoxin fluorocitrate  0   *Citrates Gliotoxin/*analogs & derivatives. J Neurophysiol 1997 Jul;78(1):295-307
KT 7595  0   Gliotoxin/*analogs & derivatives. Br J Cancer 1997;76(8):1001-10
bisdethiobis(methylthio)gliotoxin  74149-38-5 Pyrazino(1,2-a)indole-1,4-dione, 2,3,5a,6,10,10a-hexahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-3,10a-bis(methylthio)-, (3R-(3alpha,5abeta,6beta,10aalpha))  Gliotoxin/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1986;34(1):340
dehydrogliotoxin  1668-07-1   Gliotoxin/*analogs & derivatives. J Am Chem Soc 95(19):6492;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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