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Galactosylceramides

More information in Books or onNLM PubMed
Definition: Cerebrosides which contain as their polar head group a galactose moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in tissue, due to a defect in beta-galactosidase, is the cause of galactosylceramide lipidosis or globoid cell leukodystrophy.      Other names Galactosyl Ceramides; Galactocerebrosides; Ceramides, Galactosyl
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-O-(galactopyranosyl)-2-hexacosanoylamino-3,3-difluoro-heptadecane  0   *Galactosylceramides. J Med Chem. 2012 Feb 9;55(3):1227-41.
3-fluoro-2-hexacosanoylamino-1-(galactopyranosyl)heptadecane  0   *Galactosylceramides. J Med Chem. 2012 Feb 9;55(3):1227-41.
alpha-S-galactosylceramide  0   *Galactosylceramides *Thiogalactosides. Clin Immunol 2011 Aug;140(2):196-207
alpha-carba-galactosylceramide  0   *Galactosylceramides. Clin Exp Immunol 2011 May;164(2):236-47
C-galactosylceramide  0   *Galactosylceramides. J Biomed Biotechnol 2010;2010:283612
2',2'-difluoro KRN7000  0   *Galactosylceramides. ChemMedChem 2009 Mar;4(3):329-34
4-deoxy-4,4-difluoro-KRN7000  0   *Galactosylceramides. Org Lett 2008 Oct 16;10(20):4433-6
4-hydroxy-3-nitrophenylgalactosylceramide  0   *Galactosylceramides. Proc Natl Acad Sci U S A 2008 Jun 17;105(24):8339-44
suppressor glycolipid S23  0   *Galactosylceramides. Arthritis Rheum 2007 Jun;56(6):1836-45
PBS 57  0   *Galactosylceramides. J Immunol Methods 2006 May 30;312(1-2):34-9
CNC-2 galactocerebroside  0   *Galactosylceramides. Chem Pharm Bull (Tokyo) 2006 Feb;54(2):260-1
alpha-galactosylceramide  0   *Galactosylceramides. Arch Histol Cytol. 2003 Dec;66(5):397-406
2-amino-1-galactopyranosyloxy-3,4-dihydroxyoctadecane  0   *Galactosylceramides. Antimicrob Agents Chemother 2004 Jun;48(6):2085-90
clarhamnoside  0   *Galactosylceramides. J Org Chem. 2004 Feb 20;69(4):1174-9
AGL 517  0   *Galactosylceramides. Exp Hematol 1997 Aug;25(9):935-44
KRN 7000  158021-47-7   *Galactosylceramides.
Pharma Action Adjuvants, Immunologic ; Antineoplastic Agents 		Oncol Res 1995;7(10-11):529-34
agelasphin 11  152139-44-1   *Galactosylceramides. Biol Pharm Bull 1996 Mar;19(3):350-3
N-lignocerylgalactosylsphingosine  0   *Galactosylceramides. Biochim Biophys Acta 1987;896(2):153
azido-galactosylceramide  0   *Azides *Galactosylceramides. Biochem Cell Biol 1986;64(7):631
biotin-galactosylceramide  0   *Galactosylceramides Biotin/*analogs & derivatives. Biochem Cell Biol 1986;64(7):631
sulfogalactocerebroside  103370-52-1   *Galactosylceramides. Clin Chim Acta 1986;156(2):179
NBD-galactosylceramide  0   *Galactosylceramides 4-Chloro-7-nitrobenzofurazan/*analogs & derivatives. Enzyme 1985;33(3):175
1-O-galactopyranosyl-N-(10-(1-pyrene-9-enedecanoyl)sphingosine)  137593-41-0   *Galactosylceramides. Biochim Biophys Acta 1984;778(2):239
N-nervonylgalactosylsphingosine  17283-91-9 15-Tetracosenamide, N-(1-((beta-D-galactopyranosyloxy)methyl)-2-hydroxy-3-heptadecenyl)-, (R-(R*,S*-(E,Z)))  *Galactosylceramides. Clin Chim Acta 1982;126(2):127
N-palmitoylgalactosylsphingosine  34324-89-5 Hexadecanamide, N-(1-((beta-D-galactopyranosyloxy)methyl)-2-hydroxy-3-heptadecenyl)-, (R-(R*,S*-(E)))  *Galactosylceramides. Biochemistry 1981;20(21):5957
galactocerebroside  0   *Galactosylceramides. Indian J Biochem Biophys 9(1):72;1972; Nature 274(5673):813;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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