encyclopedia of medical concepts
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Ficusin
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Definition
: A naturally occurring furocoumarin, found in PSORALEA. After photoactivation with UV radiation, it binds DNA via single and double-stranded cross-linking.
do not confuse X ref PSORALEN, this specific drug, with PSORALENS;
Pharmacological Action
Anthelmintics
;
Cross-Linking Reagents
;
Photosensitizing Agents
Other names
Psoralen; Psoralene
Substance
CAS Registry & name
Categories
Source
Drugs
*
pyridazino(4,3-
h)psoralen
0
*Ficusin
*Pyridazines.
Bioorg Med Chem Lett 2009 May 15;19(10):2874-6
5-
methoxy-
8-
(3''-
hydroxymethyl-
but-
2''-
enyloxy)-
psoralen
0
*Ficusin.
Phytochemistry. 2005 Mar;66(6):649-52
5-
(4-
phenylbutoxy)psoralen
0
*Ficusin.
Pharmazie. 2005 Mar;60(3):225-8
5-
(3-
Phenylpropoxy)psoralen
0
*Ficusin.
Pharmazie. 2005 Mar;60(3):225-8
alpha-
methylene-
gamma-
butyrolactone-
psoralen
0
*Lactones
Ficusin.
Bioorg Med Chem. 2004 Jul 1;12(13):3619-25
psoberan
52810-75-0
*Ficusin
Drug Combinations.
Farmatsiia 27(4):54;1978