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Emodin

More information in Books or onNLM PubMed
Definition: Purgative anthraquinone found in several plants, especially Rhamnus frangula. It was formerly used as a laxative, but is now used mainly as tool in toxicity studies.  SCR term for aloe emodin is also available; emodin from aloe goes here not under aloe emodin   
Pharmacological Action Cathartics; Protein Kinase Inhibitors 		Other names Archin; Emodin, Rheum; Emodin, Frangula; Frangulic Acid; Rheum Emodin; Frangula Emodin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-hydroxyaloin A  0   Emodin/*analogs & derivatives. Org Lett. 2010 Dec 17;12(24):5632-5
4-aminoethylamino-emodin  0   Emodin/*analogs & derivatives. J Cell Mol Med. 2010 Jun;14(6A):1276-93
6-azidomethyl-1-hydroxy-3,8-dimethoxy-9,10-anthraquinone  0   *Azides Emodin/*analogs & derivatives Apoptosis. Mol Cancer Ther 2008 Ther;2008 Jun;7(6):1688-97
deacetyllittoraloin  0   Emodin/*analogs & derivatives Aloe. Phytochem Anal. 2003 Sep-Oct;14(5):275-80
10-hydroxyaloin B  0   Emodin/*analogs & derivatives Aloe. Phytochem Anal. 2003 Sep-Oct;14(5):275-80
aloe-emodin 1-O-glucopyranoside  0   *Glucosides Emodin/*analogs & derivatives. Bioorg Med Chem Lett 2000 Feb 21;10(4):323-7
10-(4-acetimdobenzylidene)-9-anthrone  0   Emodin/*analogs & derivatives Protein-Tyrosine Kinases/antagonists & inhibitors. Oncogene 1998 Jun 4;16(22):2855-63
2-hydroxychrysophanol  58322-78-4   Emodin/*analogs & derivatives Plant Extracts. J Nat Prod 1989;52(3):660
aloe emodin anthrone  6247-99-0   Emodin/*analogs & derivatives. Pharm Acta Helv 1989;64(1):8
1,3,8-trihydroxy-6-hydroxymethylanthraquinone  481-73-2   Emodin/*analogs & derivatives. Mutat Res 1987;180(2):147
2-hydroxyemodin  641-90-7   Emodin/*analogs & derivatives. Toxicol Lett 1987;37(2):149
emodin anthrone  491-60-1   Emodin/*analogs & derivatives. Antimicrob Agents Chemother 1986;30(1):147
questin  3774-64-9   Emodin/*analogs & derivatives Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1986;20(10):778
physcione  521-61-9 1,8-dihydroxy-3-methoxy-6-methylanthraquinone  Emodin/*analogs & derivatives.
alloin  8015-61-0 10-(1,5'-anhydroglucosyl)aloe-emodin-9-anthrone  Emodin/*analogs & derivatives Aloe.
Pharma Action Cathartics 		Curr Therap Res 16(8):817;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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