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Cobra Cardiotoxin Proteins

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Definition: Most abundant proteins in COBRA venom; basic polypeptides of 57 to 62 amino acids with four disulfide bonds and a molecular weight of less than 7000; causes skeletal and cardiac muscle contraction, interferes with neuromuscular and ganglionic transmission, depolarizes nerve, muscle and blood cell membranes, thus causing hemolysis.  /antag permitted but consider also ANTIVENINS    Other names Direct Lytic Factors; Cobra Cardiotoxin; Toxin Gamma, Cobra; Polypeptide, Cardiotoxin-Like Basic; Lytic Factors, Direct; Elapid Cardiotoxins; Cytotoxin Proteins, Cobra; Cardiotoxin, Cobra; Cardiotoxin Like Basic Polypeptide; Basic Polypeptide, Cardiotoxin-Like; Cytotoxin-Like Basic Protein (Cobra Venom); Cardiotoxin Proteins, Cobra; Cobra Venom Cardiotoxin D; Cobra Toxin Gamma; Cobra Cytotoxin Proteins; Cardiotoxins, Elapid; Cardiotoxin-Like Basic Polypeptide; Cardiotoxin VII2; Cardiotoxin VII 4; Cardiotoxin II
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cardiotoxin 3, Naja naja atra  0   *Cobra Cardiotoxin Proteins. Toxicon 2010 Jun 15;55(7):1387-95
toxin-gamma protein, Naja nigricollis  0   *Cobra Cardiotoxin Proteins. J Cell Mol Med 2009 Aug;13(8B):1695-705
Natratoxin, Naja atra  0   *Cobra Venoms Cobra Cardiotoxin Proteins. Proteins. 2008 Aug;72(2):673-83
L1AD3 peptide, Naja naja atra  0   *Cobra Cardiotoxin Proteins. Arch Biochem Biophys 2004 Dec 1;432(1):88-101
TA-ctx-like protein, Bungarus multicinctus  0   *Cobra Cardiotoxin Proteins. Biochem Mol Biol Int 1996 Dec;40(6):1271-6
cardiotoxin, crotoxin drug combination  0   *Crotoxin *Cobra Cardiotoxin Proteins Drug Combinations. Invest New Drugs 1993 May-Aug;11(2-3):151-9
cardiotoxin V  0   *Cobra Cardiotoxin Proteins Cobra Venoms. Biochemistry 1993 Aug 10;32(31):8036-44
cardiotoxin III, Naja naja atra  0   *Cobra Cardiotoxin Proteins Cobra Venoms. Biochem Mol Biol Int 1993 Apr;29(6):1015-22
Naja cardiotoxin, tris(3-nitrotyrosine-22,25,51)  0   *Cobra Cardiotoxin Proteins. Int J Biochem 1987;19(1):9
Naja cardiotoxin, bis(3-nitrotyrosine-22,51)  0   *Cobra Cardiotoxin Proteins. Int J Biochem 1987;19(1):9
cobramine B  12777-56-9   *Cobra Cardiotoxin Proteins. Arch Biochem Biophys 156(1):71;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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